Evidence map›Paper›PMID 30351254›Full record

ArticleRadiology2019

Diagnosis of Pulmonary Hypertension with Cardiac MRI: Derivation and Validation of Regression Models.

Christopher S Johns, David G Kiely, Smitha Rajaram, Catherine Hill, Steven Thomas, Kavitasagary Karunasaagarar, Pankaj Garg, Neil Hamilton, Roshni Solanki, David A Capener and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Advances in the imaging of pulmonary hypertension.International journal of cardiology. Congenital heart disease · 2025
    Review
  8. Review
  9. A Non-Invasive Approach to Pulmonary Hypertension.Journal of clinical medicine · 2025
    Review
  10. Article
  11. Article
  12. Characterization of pulmonary arterial stiffness using cardiac MRI.The international journal of cardiovascular imaging · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Christopher S JohnsFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.ORCID 0000-0003-3724-0430
David G KielyFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Smitha RajaramFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Catherine HillFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Steven ThomasFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Kavitasagary KarunasaagararFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Pankaj GargFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Neil HamiltonFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Roshni SolankiFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
David A CapenerFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Charles ElliotFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Ian SabroeFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Athanasios CharalamopopoulosFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Robin CondliffeFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
James M WildFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Andrew J SwiftFrom the Academic Department of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Rd, Sheffield S10 2JF, England (C.S.J., P.G., R.S., D.A.C., J.M.W., A.J.S.); and Sheffield Pulmonary Vascular Disease Unit (D.G.K., S.R., N.H., C.E., I.S., A.C., R.C.) and Department of Radiology (C.S.J., C.H., S.T., K.K., A.J.S.), Sheffield Teaching Hospitals, Sheffield, England.
Royal Hallamshire Hospital · GB

Funding

British Heart Foundation SP/14/6/31350Department of Health NIHR-RP-R3-12-027Medical Research Council MC_PC_16058Medical Research Council MR/M008894/1Wellcome TrustWellcome Trust 205188/Z/16/Z
6 · The paper itself

Abstract

Purpose To derive and test multiparametric cardiac MRI models for the diagnosis of pulmonary hypertension (PH). Materials and Methods Images and patient data from consecutive patients suspected of having PH who underwent cardiac MRI and right-sided heart catheterization (RHC) between 2012 and 2016 were retrospectively reviewed. Of 2437 MR images identified, 603 fit the inclusion criteria. The mean patient age was 61 years (range, 18-88 years; mean age of women, 60 years [range, 18-84 years]; mean age of men, 62 years [range, 22-88 years]). In the first 300 patients (derivation cohort), cardiac MRI metrics that showed correlation with mean pulmonary arterial pressure (mPAP) were used to create a regression algorithm. The performance of the model was assessed in the 303-patient validation cohort by using receiver operating characteristic (ROC) and χ

Indexed as

Regression AnalysisAdolescentAdultAgedAged, 80 and overCardiac CatheterizationFemaleHumansHypertension, PulmonaryImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedModels, CardiovascularPulmonary ArteryRetrospective Studies

Identifiers

PMID30351254
PMCPMC6314564
OpenAlexW2897214683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.