ArticlePulmonary circulation
Cardiac arrest and pulmonary hypertension in scurvy: a case report.
Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Vitamin deficiency, a neglected risk factor for post-anesthesia complications: a systematic review.European journal of medical research · 2025Pooled it
- Vitamin C deficiency can lead to pulmonary hypertension: a systematic review of case reports.BMC pulmonary medicine · 2024Pooled it
- Addressing micronutrient deficiencies and vitamin metabolism disorders in pediatric pulmonary hypertension: a strategic proposal for low- and middle-income countries.Frontiers in cardiovascular medicine · 2026Review
- Article
- Scurvy, all the faces you can see: our experience and review of the literature.Italian journal of pediatrics · 2025Review
- Scurvy, a not obsolete disorder: Clinical report in eight young children and literature review.Open medicine (Warsaw, Poland) · 2025Review
- Case Report: severe pulmonary hypertension in a child with micronutrient deficiency.Frontiers in pediatrics · 2025Article
- What Do We C in Children With Scurvy? A Case Series Focused on Musculoskeletal Symptoms.Hospital pediatrics · 2024Article
- Reversible severe pulmonary hypertension related to scurvy in children.BMC cardiovascular disorders · 2024Article
- Reversible severe pulmonary hypertension and right heart failure with cardiogenic shock due to scurvy: a case report.European heart journal. Case reports · 2023Article
- Scurvy-induced pulmonary arterial hypertension.BMJ case reports · 2023Article
- Case 2-2022: An Adolescent Male in Cardiac Arrest 3 Days After Liver Transplantation for End-Stage Liver Disease.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2022Article
- Pulmonary hypertensive crisis in children with pulmonary arterial hypertension undergoing cardiac catheterization.Pulmonary circulation · 2022Article
- Case report: Pulmonary hypertensive crisis leading to cardiac arrest during endoscopic evaluation in a 6-year-old boy with autism, severe malnutrition, and undiagnosed scurvy.Frontiers in pediatrics · 2022Article
- Case Report: Vitamin C combined with multiple micronutrient deficiencies is associated with pulmonary arterial hypertension in children with autistic spectrum disorder.Frontiers in nutrition · 2022Article
- Multivalve dysfunction and cardiogenic shock linked to scurvy: A case report.Anatolian journal of cardiology · 2021Article
- Impact of Nutrition on Pulmonary Arterial Hypertension.Nutrients · 2020Review
- Reversible Pulmonary Hypertension Secondary to Scurvy in a Patient with a Psychiatric Disorder: a Case Report and Literature Review.European journal of case reports in internal medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of a six-year-old boy who presented after a cardiac arrest, likely due to a pulmonary hypertensive crisis in the setting of vitamin C deficiency. After initially presenting with subacute multifocal bone lesions of unknown etiology, he experienced a pulseless electrical activity cardiac arrest while undergoing a diagnostic procedure under sedation. During his post-arrest convalescence, he developed persistent tachycardia and peripheral edema. An echocardiogram revealed findings consistent with significant pulmonary arterial hypertension, which was found to be responsive to inhaled nitric oxide. Laboratory investigation revealed undetectable levels of vitamin C, resulting in disclosure of a history of severe restrictive eating behavior. With ascorbate supplementation, the patient's pulmonary vasodilators were weaned and discontinued. Given his complete recovery, we suspect that the cardiac arrest and pulmonary hypertension were the consequence of a rare, but reversible, complication of scurvy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.