ArticleThe American journal of tropical medicine and hygiene2018
The Effect of School Closure on Hand, Foot, and Mouth Disease Transmission in Singapore: A Modeling Approach.
Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Epidemiological trends of hand, foot, and mouth disease in children under age 10, Jiangning District, Jiangsu, China (2009-2023).BMC infectious diseases · 2025Article
- Impact of non-pharmacological interventions on incidence of hand, foot and mouth disease during the COVID-19 pandemic: a large population-based observational study.BMC infectious diseases · 2024Observational
- Enterovirus A71 and coxsackievirus A6 circulation in England, UK, 2006-2017: A mathematical modelling study using cross-sectional seroprevalence data.PLoS pathogens · 2024Article
- Enterovirus-A71 exploits RAB11 to recruit chaperones for virus morphogenesis.Journal of biomedical science · 2024Article
- Seroprevalence of human enterovirus A71 in Guangzhou, China, 2019-2021.Biosafety and health · 2023Article
- Research on hand, foot and mouth disease incidence forecasting using hybrid model in mainland China.BMC public health · 2023Article
- Assessing the impact of COVID-19 interventions on the hand, foot and mouth disease in Guangdong Province, China: a Bayesian modeling study.Frontiers in public health · 2023Article
- Impact of meteorological factors on the incidence of hand-foot-mouth disease in Yangzhou from 2017 to 2022: a time series study.Frontiers in public health · 2023Article
- Effects of different levels of non-pharmaceutical interventions on hand, foot and mouth disease in Guangzhou, China.BMC public health · 2022Article
- The secular trend of enterovirus A71 after the implementation of preventive measures in Taiwan.BMC public health · 2022Article
- Impact of the coronavirus disease 2019 interventions on the incidence of hand, foot, and mouth disease in mainland China.The Lancet regional health. Western Pacific · 2022Article
- Analysis of HFMD Transmissibility Among the Whole Population and Age Groups in a Large City of China.Frontiers in public health · 2022Article
- Control measures during the COVID-19 outbreak reduced the transmission of hand, foot, and mouth disease.Journal of safety science and resilience = An quan ke xue yu ren xing (Ying wen) · 2021Article
- Molecular Epidemiological Study of Hand, Foot, and Mouth Disease in a Kindergarten-Based Setting in Bangkok, Thailand.Pathogens (Basel, Switzerland) · 2021Article
- Trend analysis and forecast of daily reported incidence of hand, foot and mouth disease in Hubei, China by Prophet model.Scientific reports · 2021Article
- Modelling lockdown and exit strategies for COVID-19 in Singapore.The Lancet regional health. Western Pacific · 2020Article
- Interventions to mitigate early spread of SARS-CoV-2 in Singapore: a modelling study.The Lancet. Infectious diseases · 2020Article
- Coronavirus Disease 2019, School Closures, and Children's Mental Health.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2020Article
- Associations between ambient air pollution and daily incidence of pediatric hand, foot and mouth disease in Ningbo, 2014-2016: a distributed lag nonlinear model.Epidemiology and infection · 2020Article
- Social approaches to COVID-19 pandemic response: effectiveness and practicality in sub-Saharan Africa.The Pan African medical journal · 2020Review
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5 authors.
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Abstract
Singapore implements a school closure policy for institutional hand, foot, and mouth disease (HFMD) outbreaks, but there is a lack of empirical evidence on the effect of closure on HFMD transmission. We conducted a retrospective analysis of 197,207 cases of HFMD over the period 2003-2012 at the national level and of 57,502 cases in 10,080 institutional outbreaks over the period 2011-2016 in Singapore. The effects of school closure due to 1) institutional outbreaks, 2) public holidays, and 3) school vacations were assessed using a Bayesian time series modeling approach. School closure was associated with a reduction in HFMD transmission rate. During public holidays, average numbers of secondary cases having onset the week after dropped by 53% (95% credible interval 44-62%), and during school vacations, the number of secondary cases dropped by 7% (95% credible interval 3-10%). Schools being temporarily closed in response to an institutional outbreak reduced the average number of new cases by 1,204 (95% credible interval 1,140-1,297). Despite the positive effect in reducing transmission, the effect of school closure is relatively small and may not justify the routine use of this measure.
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