Evidence map›Paper›PMID 30350750›Full record

ArticlePopulation studies2019

Environmental bottlenecks in children's genetic potential for adult socio-economic attainments: Evidence from a health shock.

Jason M Fletcher

Abstract read
In one paragraph

Article in Population studies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jason M Fletchera University of Wisconsin-Madison.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Statistical Data Enclave CoreP30AG017266 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1999 to 2026
$17.0M
Creating a National Resource for Genetic Research in Behavioral & Health SciencesRC2AG036495 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEIR, DAVID R. · 2009 to 2010
$7.4M
Expanding a National Resource for Genetic Research in Behavioral & Health ScienceRC4AG039029 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEIR, DAVID R. · 2010 to 2010
$6.0M
Scientific and Technical CoreP2CHD047873 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine J. Curtis · 2014 to 2026
$5.1M
Social Demographic Moderation of Genome Wide Associations for Body Mass IndexR01HD060726 · NICHD · UNIVERSITY OF COLORADO · PI BOARDMAN, JASON D, MCQUEEN, MATTHEW B · 2010 to 2014
$2.7M
NIA NIH HHS P30 AG017266NIA NIH HHS RC2 AG036495NIA NIH HHS RC4 AG039029NIA NIH HHS U01 AG009740NICHD NIH HHS P2C HD047873NICHD NIH HHS R01 HD060726
6 · The paper itself

Abstract

This paper explores gene-environment interactions-interactions between family environments and children's genetic predispositions-in determining educational attainment. The central question is whether poor childhood family environments reduce children's ability to leverage their genetic gifts to achieve high levels of educational attainment-are there important 'bottlenecks' for poor children? The multigenerational information and genetic data contained in the United States' Health and Retirement Study are used to separate two mechanisms for intergenerational transmission of socio-economic status: genetic endowments and family environments. Using parental in utero exposure to the 1918-19 influenza pandemic as a source of quasi-experimental variation in family environments (that did not affect children's genetic endowments), I estimate interactions between parental investments and children's genetic potential. The main finding suggests that girls with high genetic potential whose fathers were exposed to influenza face reduced educational attainments-a gene-environment interaction-but there is no similar effect for boys.

Indexed as

Educational StatusGene-Environment InteractionGenotypeGrandparentsIntergenerational RelationsParentsAdolescentAdultChildChild, PreschoolEconomic StatusFemaleHumansInfantInfant, NewbornMaleeducational attainmentfoetal originsgene–environment interactionsmultigenerational analysissocial mobility

Identifiers

PMID30350750
PMCPMC6472960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.