ArticleLangmuir : the ACS journal of surfaces and colloids2018
Dynamic Interactions between Lipid-Tethered DNA and Phospholipid Membranes.
Article in Langmuir : the ACS journal of surfaces and colloids, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Martini 3 Coarse-Grained Model of DNA for Heterogeneous Molecular Systems.bioRxiv : the preprint server for biology · 2026Article
- Organization and Triggered Release of Liposomes with DNA-Based Synthetic Condensates.ACS nano · 2026Article
- Cation-Controlled Assembly, Activity, and Organization of Biomimetic DNA Receptors in Synthetic Cell Membranes.Journal of the American Chemical Society · 2025Article
- Sphingomyelin regulates the transcriptional machinery in nuclear lipid microdomains.Communications biology · 2025Article
- On-the-Fly Microfluidic Control of Giant Vesicle Compositions Validated by DNA Surface Charge Sensors.ACS nano · 2025Article
- Molecular mechanocytometry using tension-activated cell tagging.Nature methods · 2023Article
- Interaction of Macromolecular Chain with Phospholipid Membranes in Solutions: A Dissipative Particle Dynamics Simulation Study.Molecules (Basel, Switzerland) · 2023Article
- Recent Advances in DNA Origami-Engineered Nanomaterials and Applications.Chemical reviews · 2023Review
- Lipid-linked nucleoside triphosphates for enzymatic synthesis of hydrophobic oligonucleotides with enhanced membrane anchoring efficiency.Chemical science · 2023Article
- Core-Shell DNA-Cholesterol Nanoparticles Exert Lysosomolytic Activity in African Trypanosomes.Chembiochem : a European journal of chemical biology · 2022Article
- Modulating membrane fusion through the design of fusogenic DNA circuits and bilayer composition.Soft matter · 2022Article
- Conjugation of chemical handles and functional moieties to DNA during solid phase synthesis with sulfonyl azides.Nucleic acids research · 2022Article
- Minimizing Cholesterol-Induced Aggregation of Membrane-Interacting DNA Origami Nanostructures.Membranes · 2021Article
- Binding of DNA origami to lipids: maximizing yield and switching via strand displacement.Nucleic acids research · 2021Article
- Hydrophobic Interactions between DNA Duplexes and Synthetic and Biological Membranes.Journal of the American Chemical Society · 2021Article
- A Biomimetic DNA-Based Membrane Gate for Protein-Controlled Transport of Cytotoxic Drugs.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2021Article
- A Biomimetic DNA-Based Membrane Gate for Protein-Controlled Transport of Cytotoxic Drugs.Angewandte Chemie (International ed. in English) · 2021Article
- Design, assembly, and characterization of membrane-spanning DNA nanopores.Nature protocols · 2021Article
- Engineering Lipid Membranes with Programmable DNA Nanostructures.Advanced biosystems · 2020Review
- Controlling aggregation of cholesterol-modified DNA nanostructures.Nucleic acids research · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Lipid-anchored DNA can attach functional cargo to bilayer membranes in DNA nanotechnology, synthetic biology, and cell biology research. To optimize DNA anchoring, an understanding of DNA-membrane interactions in terms of binding strength, extent, and structural dynamics is required. Here we use experiments and molecular dynamics (MD) simulations to determine how the membrane binding of cholesterol-modified DNA depends on electrostatic and steric factors involving the lipid headgroup charge, duplexed or single-stranded DNA, and the buffer composition. The experiments distinguish between free and membrane vesicle-bound DNA and thereby reveal the surface density of anchored DNA and its binding affinity, something which had previously not been known. The K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.