SynthesisClinical cardiology2018
Suspicious index in Lyme carditis: Systematic review and proposed new risk score.
Synthesis in Clinical cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Suspicious index in Lyme carditis: Systematic review and proposed new risk score.Clinical cardiology · 2018Pooled it
- Persistent bradycardia requiring temporary pacing in a young adult with lyme carditis: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Fulminant Lyme Carditis With Rapid Hemodynamic Deterioration in an Adolescent: A Case Report.Cureus · 2026Article
- Lyme Carditis Beyond Atrioventricular Block: Cardiac Arrest and Transient Atrial Fibrillation With Preserved Atrioventricular Conduction.Case reports in cardiology · 2026Article
- High-grade Atrioventricular Block Due to Disseminated Lyme Disease Requiring Permanent Pacemaker Implantation.US cardiology · 2026Article
- Long-term Cardiac Sequelae in Lyme Carditis: A Review.Current cardiology reviews · 2026Review
- Comparison of the Serodiagnostic Accuracy Tests for Lyme Disease in Adults and Children: A Network Meta-Analysis.Pathogens (Basel, Switzerland) · 2025Review
- Lyme Carditis Causing Polymorphic Ventricular Tachycardia and Cardiogenic Shock.JACC. Case reports · 2025Article
- Lyme Carditis With Complete Heart Block.Cureus · 2025Article
- Lyme Carditis Presenting As Idiopathic Myocarditis: Prompt Empirical Treatment Despite Negative Serology.CJC open · 2025Article
- Cardiac Magnetic Resonance Imaging in Lyme Carditis-A Case Series and Review of Literature.Journal of cardiovascular development and disease · 2024Review
- Lyme Carditis: An Infectious Cause of Atrioventricular Block - A Case Report.Arquivos brasileiros de cardiologia · 2024Article
- Successful permanent pacemaker explantation after diagnosis and treatment of Lyme carditis complete heart block: a case report.European heart journal. Case reports · 2023Article
- Lyme carditis-induced sinoatrial dysfunction after initiation of targeted oral antibiotic therapy: A case report.HeartRhythm case reports · 2023Article
- Lyme carditis presenting with accelerated junctional rhythm in an adult patient.HeartRhythm case reports · 2023Article
- A Practical Ambulatory Approach to Atrioventricular Block Secondary to Lyme Carditis.The Journal of innovations in cardiac rhythm management · 2023Article
- An Ambulatory Approach to Atrioventricular Block in Lyme Carditis Using Temporary Permanent Pacemakers.The Journal of innovations in cardiac rhythm management · 2023Article
- Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis.IDCases · 2023Article
- Prevalence of Lyme Carditis in Patients with Atrioventricular Blocks.International journal of environmental research and public health · 2022Article
- Highlighting Infranodal Block in Lyme Carditis.Texas Heart Institute journal · 2022Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLyme carditis (LC), an early manifestation of Lyme disease that most commonly presents as high-degree atrioventricular block (AVB), usually resolves with antibiotic treatment. When LC is not identified as the cause of AVB, a permanent pacemaker may be inappropriately implanted in a reversible cardiac conduction disorder. HYPOTHESIS: The likelihood that a patient's high-degree AVB is caused by LC can be evaluated by clinical characteristics incorporated into a risk stratification tool.
methodsA systematic review of all published cases of LC with high-degree AVB, and five cases from the authors' experience, was conducted. The results informed the development of a new risk stratification tool, the Suspicious Index in LC (SILC) score. The SILC score was then applied to each case included in the review.
resultsOf the 88 cases included, 51 (58%) were high-risk, 31 (35.2%) intermediate-risk, and 6 (6.8%) low-risk for LC according to the SILC score (sensitivity 93.2%). For the subset of 32 cases that reported on all SILC variables, 24 (75%) cases were classified as high-risk, 8 (25%) intermediate-risk, and 0 low-risk (sensitivity 100%). Specificity could not be assessed (no control group). Notably, 6 of the 11 patients who received permanent pacemakers had reversal of AVB with antibiotic treatment.
conclusionThe SILC risk score and COSTAR mnemonic (constitutional symptoms; outdoor activity; sex = male; tick bite; age < 50; rash = erythema migrans) may help to identify LC in patients presenting with high-degree AVB, and ultimately, minimize the implantation of unnecessary permanent pacemakers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.