Evidence map›Paper›PMID 30350358›Full record

SynthesisClinical cardiology2019

Transcatheter aortic valve replacement in patients with pure native aortic valve regurgitation: A systematic review and meta-analysis.

Abdullah Haddad, Remy Arwani, Osama Altayar, Tarek Sawas, M Hassan Murad, Eduardo de Marchena

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. First-in-human TAVR With Navitor Self-expanding Intra-annular Valve in LVAD-Associated Aortic Regurgitation.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Abdullah HaddadDivision of Cardiology, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania. Harvard T.H Chan School of Public Health, Boston, Massachusetts.ORCID https://orcid.org/0000-0002-6984-4717
Remy ArwaniAin Shams University-Faculty of Medicine, Cairo, Egypt.
Osama AltayarDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Tarek SawasDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.
M Hassan MuradEvidence-based Practice Center, Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota.
Eduardo de MarchenaDivision of Cardiology, University of Miami-Miller School of Medicine, Miami, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis sought to summarize the available evidence on the use of transcatheter aortic valve replacement (TAVR) in patients with Native Aortic Valve Regurgitation (NAVR) and compare outcomes between first and second generation valves. Owing to the improvements in transcatheter heart valve design and procedural success, TAVR has become increasingly performed in broader aortic valve pathologies. We searched Medline, Embase, Cochrane, and Scopus databases from 2007 to 2018 and performed a systematic review on reports with at least 10 patients with aortic valve regurgitation undergoing TAVR procedure. The main outcome of interest was all-cause mortality at 30 days. A total of 638 patients across 12 studies were included. Mean age ranged from 68 to 84. Society of Thoracic Surgeons score ranged from 5.4% to 13.1% and Logistic EuroSCORE ranged from 18.2% to 33%. The incidence rate of all-cause mortality at 30 days was found to be 11% (95% CI 7%-16%; I

Indexed as

Aortic ValveAortic Valve InsufficiencyCause of DeathGlobal HealthHumansTranscatheter Aortic Valve ReplacementTreatment Outcomeaortic regurgitationmeta-analysissystematic reviewtranscatheter aortic valve replacement

Identifiers

PMID30350358
PMCPMC6436518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.