ArticlePsychopharmacology2019
Lack of consistent sex differences in D-amphetamine-induced dopamine release measured with [
Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Hormonal contraceptives and the brain: A systematic review on 60 years of neuroimaging, EEG, and biochemical studies in humans and animals.Frontiers in neuroendocrinology · 2023Pooled it
- The Effects of Hormonal Contraceptives on the Brain: A Systematic Review of Neuroimaging Studies.Frontiers in psychology · 2020Pooled it
- Sexual dimorphism of midbrain catecholaminergic metabolism revealed by neuromelanin-sensitive MRI.Molecular psychiatry · 2026Article
- Sex differences in the response to treatment of attention deficit hyperactivity disorder.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Striatal dopamine synthesis and cognitive flexibility differ between hormonal contraceptive users and nonusers.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect.Pharmacological reviews · 2023Review
- Sex Differences in Psychosis: Focus on Animal Models.Current topics in behavioral neurosciences · 2023Review
- Catechol-O-Methyltransferase Effects on Smoking: A Review and Proof of Concept of Sex-Sensitive Effects.Current behavioral neuroscience reports · 2022Article
- Sex-Dependent Alterations in the mRNA Expression of Enzymes Involved in Dopamine Synthesis and Breakdown After Methamphetamine Self-Administration.Neurotoxicity research · 2022Article
- Subjective and Cardiovascular Responses to an Acute Laboratory Gambling Task in Men and Women.Frontiers in psychiatry · 2022Article
- Evaluating the evidence for sex differences: a scoping review of human neuroimaging in psychopharmacology research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
- Functional dynamics of dopamine synthesis during monetary reward and punishment processing.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- Sex and the dopaminergic system: Insights from addiction studies.Handbook of clinical neurology · 2020Review
- Response to the letter concerning the publication: Amyloid pathology fingerprint differentiates post-traumatic stress disorder and traumatic brain injury. Mohamed AZ, et al. NeuroImage Clinical 2018 June 5;19:716-726.NeuroImage. Clinical · 2019Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
rationaleSex differences in the dopaminergic response to psychostimulants could have implications for drug abuse risk and other psychopathology involving the dopamine system, but human data are limited and mixed.
objectivesHere, we sought to investigate sex differences in dopamine release after oral D-amphetamine administration.
methodsWe used [
resultsUsing both a priori anatomical regions of interest based on previous findings and voxelwise analyses, we failed to consistently detect broad sex differences in D-amphetamine-induced dopamine release. Nevertheless, there was limited evidence for greater right ventral striatal dopamine release in young adult males relative to similarly aged females, but this was not consistently observed across samples. Plasma estradiol did not correlate with dopamine release and this measure did not differ in females on and off hormonal birth control.
conclusionsWhile our finding in young adults from one dataset of greater %ΔBP
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.