ArticleSurgical endoscopy2019
Clinical outcomes of endoscopic resection for colorectal laterally spreading tumors with advanced histology.
Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Precut mucosectomy versus endoscopic resection techniques for colorectal lesions sized 10-30 mm: meta-analysis and systematic review.Surgical endoscopy · 2025Pooled it
- Pooled it
- Endoscopic submucosal dissectionWorld journal of gastroenterology · 2021Pooled it
- Review
- Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes.World journal of gastrointestinal endoscopy · 2025Article
- Technical Advances in Endoscopic Resection Techniques for Lower GI Malignancies.Visceral medicine · 2024Review
- Endoscopic resection for colorectal laterally spreading tumors in East Asian countries: a systematic review.Translational cancer research · 2022Review
- Is underwater endoscopic mucosal resection of colon polyps superior to conventional techniques? A network analysis of endoscopic mucosal resection and submucosal dissection.Endoscopy international open · 2022Article
- Blue laser imaging combined with JNET (Japan NBI Expert Team) classification for pathological prediction of colorectal laterally spreading tumors.Surgical endoscopy · 2021Article
- The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors.Gastroenterology research and practice · 2020Article
- Clinical outcomes and risk factors of post-polypectomy microperforation in patients with colorectal neoplasia: a case-control study.Therapeutic advances in gastrointestinal endoscopyArticle
- Modified endoscopic mucosal resection techniques for treating precancerous colorectal lesions.Annals of gastroenterologyReview
- Emerging endoscopic resection strategies for organ preservation in early colorectal cancer.Annals of gastroenterologyReview
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColorectal laterally spreading tumors (LSTs) are large, flat neoplasms that are usually treated using different endoscopic techniques based on their morphology, size, and histology. The aim of this study was to evaluate the clinical outcomes of LSTs with advanced histology treated by endoscopic resection.
methodsA total of 246 LSTs with advanced histology [i.e., high-grade dysplasia (HGD) and adenocarcinoma (AC)] treated by endoscopic resection [i.e., endoscopic mucosal resection (EMR), EMR-precutting (EMR-P), and endoscopic submucosal dissection (ESD)] were enrolled. Clinicopathological characteristics were collected by review of patient's medical records.
resultsThe en bloc resection and R0 resection rates were 75.6% and 85.0%, respectively. The bleeding and perforation rates were 10.2% and 2.4%, respectively. The frequency of cancerous pit pattern and bleeding was significantly higher in LSTs with AC than in LSTs with HGD. The R0 resection rate in LSTs with HGD was significantly higher than that in LSTs with AC. The frequency of cancerous pit patterns in LST cases with submucosal AC was significantly higher than those with intramucosal AC. The mean size of the LSTs was significantly larger in ESD group than in EMR or EMR-P groups. The frequencies of nodular mixed subtype, cancerous pit patterns, and en bloc resection rates were significantly higher in the ESD group than in the EMR or EMR-P groups. However, the frequency of perforation was significantly higher in EMR-P group than in EMR or ESD groups.
conclusionsThese results indicate that ESD is a more acceptable treatment approach for resection of colorectal LSTs of larger size, with nodular mixed subtype, having a cancerous pit pattern or AC, using either en bloc or curative resection methods, compared to EMR or EMR-P procedures.
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