Evidence map›Paper›PMID 30350010›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2019

Francesco Ceci, Paolo Castellucci, Tiziano Graziani, Andrea Farolfi, Cristina Fonti, Filippo Lodi, Stefano Fanti

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prospective Evaluation of PSMA-TargetedJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Size and SUVThe Prostate · 2025
    Article
  11. Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto™.European journal of nuclear medicine and molecular imaging · 2024
    Article
  12. Comparison of digital and analog [Scientific reports · 2024
    Article
  13. Advances in Prostate Cancer Biomarkers and Probes.Cyborg and bionic systems (Washington, D.C.) · 2024
    Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Event-free survival afterEuropean journal of nuclear medicine and molecular imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Francesco CeciMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy. francesco.ceci3@unibo.it.ORCID http://orcid.org/0000-0001-9785-5248
Paolo CastellucciMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
Tiziano GrazianiMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
Andrea FarolfiMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
Cristina FontiMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
Filippo LodiMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
Stefano FantiMetropolitan Nuclear Medicine of Bologna, University of Bologna, Bologna, Italy.
University of Bologna · ITUCLA Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe primary objective was the evaluation of Gallium 68 ( MATERIAL AND

methodsThis population was enrolled through a prospective, open label, single-center trial performed at the Nuclear Medicine of the University Hospital of Bologna (Eudract: 2015-004589-27 OsSC). The inclusion criteria were: (1) proven PCa, (2) surgery or radiotherapy as definitive therapy, (3) proven BCR, (4) prostate-specific antigen (PSA) 0.2-2 ng/ml, (5) age ≥ 35 years, and 6() willing to sign an informed consent. Three-hundred and thirty-two (332) patients were enrolled between March 2016 and June 2017; mean/median PSA was 0.84/0.61 ng/ml, 97.9% (325/332) of patients received radical prostatectomy and 2.1% (7/332) radiotherapy. Different patterns of BCR were identified by referent physicians as follows: (a) persisting detectable PSA after radical prostatectomy in 13.5% (45/332) of patients (subgroup 1), (b) first-time PSA failure after radical therapy in 44.9% (149/332) (subgroup 2), and (c) PSA increase after salvage or hormonal therapy in 41.6% (138/332) (subgroup 3).

resultsPrimary objective:

conclusionOur data confirmed the efficacy of

Indexed as

OligopeptidesPositron Emission Tomography Computed TomographyAgedAged, 80 and overEdetic AcidGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingProspective StudiesProstate-Specific AntigenProstatic NeoplasmsTreatment FailureEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptidesProstate-Specific AntigenBiochemical recurrenceFirst biochemical recurrenceProstate cancerPSMA PET/CTPSMA prospectivePSMA prostate

Identifiers

PMID30350010
OpenAlexW2896566817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.