Evidence map›Paper›PMID 30349994›Full record

ReviewCurrent genetics2019

Genetic mechanisms of arsenic detoxification and metabolism in bacteria.

Ge Yan, Xingxiang Chen, Shiming Du, Zixin Deng, Lianrong Wang, Shi Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 124 citations in OpenAlex.

  1. The Genomic Characterization of a NovelInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Degradation of Benzo[a]pyrene byMicroorganisms · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Indian journal of microbiology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Arsenite tolerance and removal potential of the indigenous halophilic bacterium, Halomonas elongata SEK2.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  17. Article
  18. Phosphate Uptake and Its Relation to Arsenic Toxicity in Lactobacilli.International journal of molecular sciences · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ge YanMinistry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan University, Wuhan, 430071, Hubei, China.
Xingxiang ChenMinistry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan University, Wuhan, 430071, Hubei, China.
Shiming DuTaihe Hospital, Hubei University of Medicine, Shiyan, 442000, Hubei, China.
Zixin DengMinistry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan University, Wuhan, 430071, Hubei, China.
Lianrong WangMinistry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan University, Wuhan, 430071, Hubei, China.
Shi ChenMinistry of Education Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan University, Wuhan, 430071, Hubei, China. shichen@whu.edu.cn.
Wuhan University · CNTaihe Hospital · CNHubei University of Medicine · CN

Funding

National Natural Science Foundation of China 31170070National Natural Science Foundation of China 31520103902National Natural Science Foundation of China 31670072National Natural Science Foundation of China 31670086National Natural Science Foundation of China 31720103906
6 · The paper itself

Abstract

Arsenic, distributed pervasively in the natural environment, is an extremely toxic substance which can severely impair the normal functions of living cells. Research on the genetic mechanisms of arsenic metabolism is of great importance for remediating arsenic-contaminated environments. Many organisms, including bacteria, have developed various strategies to tolerate arsenic, by either detoxifying this harmful element or utilizing it for energy generation. This review summarizes arsenic detoxification as well as arsenic respiratory metabolic pathways in bacteria and discusses novel arsenic resistance pathways in various bacterial strains. This knowledge provides insights into the mechanisms of arsenic biotransformation in bacteria. Multiple detoxification strategies among bacteria imply possible functional relationships among different arsenic detoxification/metabolism pathways. In addition, this review sheds light on the bioremediation of arsenic-contaminated environments and prevention of antibiotic resistance.

Indexed as

ArsenicBacteriaBiotransformationInactivation, MetabolicArsenicArsenic biotransformationArsenic detoxificationArsenic metabolismArsenic resistanceBacteria

Identifiers

PMID30349994
OpenAlexW2897775881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.