Evidence map›Paper›PMID 30349976›Full record

ArticleInternational journal of computer assisted radiology and surgery2019

Multimodal image registration for liver radioembolization planning and patient assessment.

Nadine Spahr, Smita Thoduka, Nasreddin Abolmaali, Ron Kikinis, Andrea Schenk

Open access · hybridAbstract read
In one paragraph

Article in International journal of computer assisted radiology and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. SPECT and CT misregistration reduction in [European journal of nuclear medicine and molecular imaging · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Generation of annotated multimodal ground truth datasets for abdominal medical image registration.International journal of computer assisted radiology and surgery · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Nadine SpahrFraunhofer Institute for Medical Image Computing, MEVIS, Lübeck, Germany. nadine.spahr@mevis.fraunhofer.de.ORCID http://orcid.org/0000-0002-9726-519X
Smita ThodukaDepartment of Radiology, Städtisches Klinikum Dresden, Dresden, Germany.
Nasreddin AbolmaaliDepartment of Radiology, Städtisches Klinikum Dresden, Dresden, Germany.
Ron KikinisFraunhofer Institute for Medical Image Computing, MEVIS, Lübeck, Germany.
Andrea SchenkFraunhofer Institute for Medical Image Computing, MEVIS, Lübeck, Germany.
Fraunhofer Institute for Digital Medicine · DEStädtisches Klinikum Dresden · DEBrigham and Women's Hospital · US

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

purposeMultimodal imaging plays a key role in patient assessment and treatment planning in liver radioembolization. It will reach its full potential for convenient use in combination with deformable image registration methods. A registration framework is proposed for multimodal liver image registration of multi-phase CT, contrast-enhanced late-phase T1, T2, and DWI MRI sequences.

methodsA chain of four pair-wise image registrations based on a variational registration framework using normalized gradient fields as distance measure and curvature regularization is introduced. A total of 103 cases of 35 patients was evaluated based on anatomical landmarks and deformation characteristics.

resultsGood anatomical correspondence and physical plausibility of the deformation fields were attained. The global mean landmark errors vary from 3.20 to 5.36 mm, strongly influenced by low resolved images in z-direction. Moderate volume changes are indicated by mean minimum and maximum Jacobian determinants of 0.44 up to 1.88. No deformation foldings were detected. The mean average divergence of the deformation fields range from 0.08 to 0.16 and the mean harmonic energies vary from 0.08 to 0.58.

conclusionThe proposed registration solutions enable the combined use of information from multimodal imaging and provide an excellent basis for patient assessment and primary planning for liver radioembolization.

Indexed as

Embolization, TherapeuticAlgorithmsBrachytherapyHumansImage Processing, Computer-AssistedLiver NeoplasmsMagnetic Resonance ImagingMultimodal ImagingPatient Care PlanningTomography, X-Ray ComputedImage registrationLiverMultimodalityRadioembolization

Identifiers

PMID30349976
PMCPMC6373337
OpenAlexW2896937008

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.