Evidence map›Paper›PMID 30349852›Full record

ArticleAnnals of clinical and translational neurology2018

Alcohol consumption and probable rapid eye movement sleep behavior disorder.

Chaoran Ma, Milena Pavlova, Junjuan Li, Ying Liu, Yujie Sun, Zhe Huang, Shouling Wu, Xiang Gao

Abstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Plasma urate concentrations and possible REM sleep behavior disorder.Annals of clinical and translational neurology · 2019
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Clinical trials in REM sleep behavioural disorder: challenges and opportunities.Journal of neurology, neurosurgery, and psychiatry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chaoran MaDepartment of Nutritional Sciences The Pennsylvania State University University Park Pennsylvania.
Milena PavlovaDepartment of Neurology Brigham and Women's Hospital Harvard Medical School Boston Massachusetts.
Junjuan LiDepartment of Nephrology Kailuan General Hospital Tangshan China.
Ying LiuDepartment of Neurology Kailuan General Hospital Tangshan China.
Yujie SunDepartment of Neurology Kailuan General Hospital Tangshan China.
Zhe HuangDepartment of Cardiology Kailuan General Hospital Tangshan China.
Shouling WuDepartment of Cardiology Kailuan General Hospital Tangshan China.
Xiang GaoDepartment of Nutritional Sciences The Pennsylvania State University University Park Pennsylvania.

Funding

Statins, statin-related gene, and Parkinson's disease riskR21NS087235 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI GAO, XIANG · 2014 to 2015
$398k
A Prospective Study of Nicotine from Edible Solanaceae and Risk of Parkinson DiseaseR03NS093245 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI GAO, XIANG · 2016 to 2017
$157k
NINDS NIH HHS R03 NS093245NINDS NIH HHS R21 NS087235
6 · The paper itself

Abstract

objectiveTo systematically examine the association between alcohol intake and likelihood of having probable rapid eye movement sleep behavior disorder (pRBD) 6 years later.

methodsThe study included 11,905 participants (mean age: 47.7 years) of the Kailuan Study, free of stroke, cancer, Parkinson disease, dementia, and head injury in 2006. We determined pRBD using a validated RBD questionnaire-Hong Kong in 2012. Amounts and types of alcohol intake were collected with questionnaire. Participants were categorized into: nondrinkers, light (women: 0-0.4 servings/day; men: 0-0.9 servings/day), moderate (women: 0.5-1.0 servings/day; men: 1-2 servings/day), and heavy drinkers(women: >1 serving/day; men: >2 servings/day). To examine the alcohol-pRBD relationship, we used logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs), adjusting for demographic characteristics, smoking, hypertension, diabetes, physical activity, body mass index, and plasma concentrations of lipids and urate.

resultsCompared with nondrinkers, current drinkers had a 23% higher likelihood of having pRBD (adjusted OR 1.23, 95% CI 1.07-1.59). Both moderate (adjusted OR: 1.53, 95% CI 1.01-2.30) and heavy drinkers (adjusted OR: 1.29, 95% CI 1.00-1.66), but not light drinkers (adjusted OR: 1.16, 95% CI 0.94-1.44), had a significantly higher likelihood of having pRBD, relative to nondrinkers. There was a nonsignificant trend between consumption of each individual alcoholic beverages (i.e., beer, wine, or hard liquor) and higher likelihood of having pRBD (adjusted ORs ranged from 1.11 to 1.49).

conclusionsAlcohol consumption was associated with a higher likelihood of having pRBD. Future prospective studies with clinically confirmed RBD, large sample size for information on types of alcoholic beverage are warranted.

Identifiers

PMID30349852
PMCPMC6186943

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.