Evidence map›Paper›PMID 30349849›Full record

ArticleAnnals of clinical and translational neurology2018

Urban air quality and associations with pediatric multiple sclerosis.

Amy M Lavery, Emmanuelle Waubant, T Charles Casper, Shelly Roalstad, Meghan Candee, John Rose, Anita Belman, Bianca Weinstock-Guttman, Greg Aaen, Jan-Mendelt Tillema and 19 more

Abstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Trial
  6. Article
  7. A narrative review of genetic and environmental factors and risk for multiple sclerosis. The design of the Italian multicentric PEDIGREE study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  8. Article
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  12. Article
  13. Article
  14. Article
  15. Review
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  18. Air pollution and multiple sclerosis: a comprehensive review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Amy M LaveryDivision of Child Neurology Children's Hospital of Philadelphia Philadelphia Pennsylvania.
Emmanuelle WaubantUniversity of California San Francisco San Francisco California.
T Charles CasperUniversity of Utah Salt Lake City Utah.
Shelly RoalstadUniversity of Utah Salt Lake City Utah.
Meghan CandeeUniversity of Utah Salt Lake City Utah.
John RoseUniversity of Utah Salt Lake City Utah.
Anita BelmanStony Brook University Stony Brook New York.
Bianca Weinstock-GuttmanBuffalo General Hospital State University of New York at Buffalo Buffalo New York.
Greg AaenLoma Linda University Children's Hospital Loma Linda California.
Jan-Mendelt TillemaMayo Clinic Rochester Minnesota.
Moses RodriguezMayo Clinic Rochester Minnesota.
Jayne NessUniversity of Alabama Tuscaloosa Alabama.
Yolanda HarrisUniversity of Alabama Tuscaloosa Alabama.
Jennifer GravesUniversity of California San Francisco San Francisco California.
Lauren KruppNew York University Medical Center New York New York.
Leigh CharvetNew York University Medical Center New York New York.
Leslie BensonBoston Children's Pediatric MS Center Boston Massachusetts.
Mark GormanBoston Children's Pediatric MS Center Boston Massachusetts.
Manikum MoodleyCleveland Clinic Cleveland Ohio.
Mary RenselCleveland Clinic Cleveland Ohio.
Manu GoyalWashington University in St. Louis St. Louis Missouri.
Soe MarWashington University in St. Louis St. Louis Missouri.
Tanuja ChitnisBrigham and Women's Hospital Harvard Medical School Boston Massachusetts.
Teri SchreinerDenver Children's Hospital Denver Colorado.
Tim LotzeTexas Children's Hospital Houston Texas.
Benjamin GreenbergUniversity of Texas Southwestern Medical Center Dallas Texas.
Ilana KahnChildren's National Medical Center Washington District of Columbia.
Jennifer RubinLurie Children's Hospital Chicago Illinois.
Amy T WaldmanDivision of Child Neurology Children's Hospital of Philadelphia Philadelphia Pennsylvania.

Funding

Environmental and genetic risk factors for pediatric MSR01NS071463 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WAUBANT, EMMANUELLE LAURENCE · 2010 to 2015
$2.8M
NINDS NIH HHS R01 NS071463
6 · The paper itself

Abstract

backgroundWe previously identified air quality as a risk factor of interest for pediatric multiple sclerosis. The purpose of this study is to more closely examine the association between the six criteria air pollutants and pediatric MS as well as identify specific areas of toxic release using data from the Toxic Release Inventory.

methodsPediatric MS cases (

resultsFine particulate matter (PM

conclusionOut of several air pollutants examined, we show that fine particulate matter and three other criteria pollutants (SO

Identifiers

PMID30349849
PMCPMC6186930

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.