ArticleSouthern African journal of HIV medicine2018
The metabolic syndrome and renal function in an African cohort infected with human immunodeficiency virus.
Article in Southern African journal of HIV medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
What it found
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Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Kidney dysfunction and associated factors among adults living with human immuno-deficiency virus in Africa: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Burden of metabolic syndrome in the global adult HIV-infected population: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Prevalence of metabolic syndrome among people living with human immunodeficiency virus in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Prevalence of the metabolic syndrome in African populations: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Effects of Two Anti-HIV-1 Regimens on Creatinine and Blood Lipids in Elderly People Living With HIV-1.AIDS research and treatment · 2026Article
- Pathogenesis of HIV-Associated Metabolic Syndrome and Clinical Management Recommendations.International journal of general medicine · 2025Review
- Weight Gain and Metabolic Syndrome in Human Immunodeficiency Virus Patients.Infection & chemotherapy · 2022Review
- Renal function in a cohort of HIV-infected patients initiating antiretroviral therapy in an outpatient setting in Ethiopia.PloS one · 2021Article
- Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Hypertension and Metabolic Syndrome in Persons with HIV.Current hypertension reports · 2020Review
- Immune Activation, Inflammation, and Non-AIDS Co-Morbidities in HIV-Infected Patients under Long-Term ART.Viruses · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe human immunodeficiency virus (HIV) is often accompanied by renal dysfunction. It is expected that metabolic syndrome (MetS) may exacerbate renal impairment.
objectiveWe therefore determined the prevalence of MetS and the association thereof with renal function in a South African cohort infected with HIV.
methodsWe matched 114 HIV-infected (77.3% on antiretroviral therapy [ART] and 22.7% ART-naïve) and 114 HIV-uninfected individuals according to age, sex and locality. We examined cardiovascular, anthropometric and metabolic measurements and determined the MetS. Renal function was assessed using standardised procedures.
resultsThe prevalence of MetS was lower in the HIV-infected individuals as compared to the uninfected individuals (28% vs. 44%,
conclusionThe HIV-infected Africans with MetS had almost twofold higher uACR, despite the low prevalence of MetS, compared to their uninfected counterparts. The combination of HIV and MetS seemed to increase the risk for renal impairment.
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Registered trials
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