Evidence map›Paper›PMID 30349737›Full record

ArticleClinical hypertension2018

Metabolic syndrome, not menopause, is a risk factor for hypertension in peri-menopausal women.

Gyu Chul Oh, Kee Soo Kang, Chan Soon Park, Ho Kyung Sung, Kyoung Hwa Ha, Hyeon Chang Kim, Sungha Park, Sang Hyun Ihm, Hae-Young Lee

Registry-linked trialAbstract read
In one paragraph

Article in Clinical hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05387174 (Nursing Intervention in Two Risk Factors of the Metabolic Syndrome, Abdominal Obesity and Arterial Hypertension, and Quality of Life in the Climacteric Period), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05387174 nacompletednot on this mapstarted 2021, after this paper: background citation

Nursing Intervention in Two Risk Factors of the Metabolic Syndrome, Abdominal Obesity and Arterial Hypertension, and Quality of Life in the Climacteric Period

TypeinterventionalSponsorUniversidad de ConcepcionRan2021 to 2021Enrolled80ConditionsObesity, Abdominal, Hypertension, Quality of Life, MenopauseArms: Nursing intervention in two risk factors of the Metabolic Syndrome, abdominal obesity and arterial hypertension and quality of life in the climacteric period.
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gyu Chul Oh *1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kee Soo Kang *3Seoul National University College of Medicine, Seoul, Korea.
Chan Soon Park1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ho Kyung Sung4Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kyoung Hwa Ha5Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
Hyeon Chang Kim6Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.
Sungha Park7Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Sang Hyun Ihm8Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea, Bucheon, Korea.
Hae-Young Lee1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been long debated whether menopause itself is a risk factor for hypertension in peri-menopausal women. We aimed to assess the association between menopause and hypertension, and whether metabolic syndrome (MetS) has an influence on its effect.

methodsData for 1502 women aged 42 to 53 from the Korean Genome and Epidemiology Study (KoGES) database were retrospectively analyzed. The KoGES database consists of 10,038 participants, of which 52.6% (5275) were female. Subjects were followed up for 4 years, and compared according to menopausal status. Additionally, 1216 non-hypertensive subjects were separately analyzed to assess whether a change in menopausal status was associated with development of hypertension.

resultsThe prevalence of hypertension, diabetes, and MetS for menopausal and non-menopausal subjects at baseline was 24.4% vs. 16.7%, 5.8% vs. 2.9%, and 25.4% vs. 16.6%, respectively (

conclusionsMenopause is closely associated with increased incidence of hypertension, but the increase may not be attributable to menopause itself but to increased prevalence of MetS.

Indexed as

HypertensionMenopauseMetabolic syndromeObesity

Identifiers

PMID30349737
PMCPMC6191993

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.