Evidence map›Paper›PMID 30349617›Full record

ArticleThe World Allergy Organization journal2018

Increasing trends of anaphylaxis-related events: an analysis of anaphylaxis using nationwide data in Taiwan, 2001-2013.

Tsung-Chieh Yao, Ann Chen Wu, Ya-Wen Huang, Jiu-Yao Wang, Hui-Ju Tsai

Open access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Who is at-risk for severe anaphylaxis in France?The World Allergy Organization journal · 2024
    Article
  3. Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024
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  9. Anaphylaxis in Brazil between 2011 and 2019.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Article
  10. Article
  11. Article
  12. Global Trends in Anaphylaxis Epidemiology and Clinical Implications.The journal of allergy and clinical immunology. In practice · 2020
    Article
  13. Advances in drug allergy, urticaria, angioedema, and anaphylaxis in 2018.The Journal of allergy and clinical immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Tsung-Chieh Yao1Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ann Chen Wu4PrecisiOn Medicine and Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA USA.
Ya-Wen Huang6Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli 350 Taiwan.
Jiu-Yao Wang7Department of Pediatrics, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hui-Ju Tsai6Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli 350 Taiwan.ORCID 0000-0002-5338-6117
National Health Research Institutes · TWBoston Children's Hospital · USChang Gung Memorial Hospital · TWNational Cheng Kung University · TW

Funding

Age-Dependent Pharmacogenomics of Asthma Treatment (ADAPT)R01HD085993 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI WU, ANN CHEN · 2016 to 2020
$3.1M
NICHD NIH HHS R01 HD085993
6 · The paper itself

Abstract

backgroundAnaphylaxis is a severe, potentially fatal, and systemic allergic reaction. Previous studies document increasing trends in incidence rates of anaphylaxis-related events in Western countries, yet little is known about the incidence and trend of anaphylaxis in Asia. In this study, we aimed to determine time trends in incidence rates of anaphylaxis-related events in Taiwan from 2001 through 2013.

methodsWe utilized medical claims data from the National Health Insurance Research Databases in Taiwan. We identified anaphylaxis-related events (ICD-9-CM-codes: 995.0, 995.60-995.69, 999.41-999.42, and 999.49) and calculated incidence rates. Poisson regression models were applied to examine trends and incidence rates.

resultsA total of 2496 patients (mean age, 45.11 years; 56% male) with first-time anaphylaxis were identified during 34,430,000 person-years of observation time. The overall incidence of anaphylaxis was 7.25 (95% confidence interval (CI) = 6.97-7.53) per 100,000 person-years, increasing from 4.79 in 2001 to 8.20 in 2013, with an incidence rate ratio (IRR) of 1.05 (95%CI = 1.04-1.06). Over the 13-year period, the increasing trends were found in incident diagnosis of anaphylaxis-related outpatient or emergency department visits (IRR = 1.06, 95%CI = 1.05-1.08) and admissions to intensive care units (IRR = 1.06, 95%CI = 1.03-1.10), whereas the trends in incidence of anaphylaxis-related hospitalizations remained steady. The proportion of patients requiring hospitalizations among all patients with anaphylaxis (

conclusionThe incidence rate of anaphylaxis in Taiwan has increased at an average rate of 5% annually since 2001, paralleling the rising trends in several Western countries.

Indexed as

AnaphylaxisAsianEpidemiologyIncidenceTime trends

Identifiers

PMID30349617
PMCPMC6178262
OpenAlexW2890735016

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.