Evidence map›Paper›PMID 30349532›Full record

ArticleFrontiers in immunology2018

Parasitic Nematodes Exert Antimicrobial Activity and Benefit From Microbiota-Driven Support for Host Immune Regulation.

Sebastian Rausch, Ankur Midha, Matthias Kuhring, Nicole Affinass, Aleksandar Radonic, Anja A Kühl, André Bleich, Bernhard Y Renard, Susanne Hartmann

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

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  15. Nematode-bacteria interactions in bovine parasitic otitis.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024
    Article
  16. Article
  17. Article
  18. Gut pathogens · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sebastian RauschDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Ankur MidhaDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Matthias KuhringBioinformatics Unit (MF 1), Robert Koch Institute, Berlin, Germany.
Nicole AffinassDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Aleksandar RadonicCentre for Biological Threats and Special Pathogens (ZBS 1), Robert Koch Institute, Berlin, Germany.
Anja A KühliPATH.Berlin, Core Unit for Immunopathology for Experimental Models, Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
André BleichInstitute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
Bernhard Y RenardBioinformatics Unit (MF 1), Robert Koch Institute, Berlin, Germany.
Susanne HartmannDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal parasitic nematodes live in intimate contact with the host microbiota. Changes in the microbiome composition during nematode infection affect immune control of the parasites and shifts in the abundance of bacterial groups have been linked to the immunoregulatory potential of nematodes. Here we asked if the small intestinal parasite

Indexed as

AnimalsBacteriaCluster AnalysisGastrointestinal MicrobiomeGenes, HelminthHost Microbial InteractionsIntestinal Diseases, ParasiticIntestine, SmallMice, Inbred C57BLNematospiroides dubiusSpecific Pathogen-Free OrganismsStrongylida InfectionsTh2 CellsT-Lymphocytes, RegulatoryTranscriptomeantimicrobialgerm-freeimmune regulationmicrobiotanematodeparasiteTh2Treg

Identifiers

PMID30349532
PMCPMC6186814

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.