Evidence map›Paper›PMID 30349523›Full record

ArticleFrontiers in microbiology2018

Andrographolide Prevents EV-D68 Replication by Inhibiting the Acidification of Virus-Containing Endocytic Vesicles.

Dongyin Wang, Haoran Guo, Junliang Chang, Dong Wang, Bin Liu, Pujun Gao, Wei Wei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. A Systematic Review on the Antimicrobial Activity of Andrographolide.Journal of microbiology and biotechnology · 2024
    Pooled it
  2. Review
  3. Andrographolide Inhibits Rabies Virus Replication.Transboundary and emerging diseases · 2026
    Article
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  5. Article
  6. Review
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  8. Article
  9. Article
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  12. Which East Asian herbal medicines can decrease viral infections?Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dongyin WangDepartment of Hepatology, The First Hospital of Jilin University, Jilin University, Changchun, China.
Haoran GuoInstitute of Virology and AIDS Research, The First Hospital of Jilin University, Changchun, China.
Junliang ChangInstitute of Virology and AIDS Research, The First Hospital of Jilin University, Changchun, China.
Dong WangDepartment of Hepatology, The First Hospital of Jilin University, Jilin University, Changchun, China.
Bin LiuDepartment of Hand Surgery, The First Hospital of Jilin University, Changchun, China.
Pujun GaoDepartment of Hepatology, The First Hospital of Jilin University, Jilin University, Changchun, China.
Wei WeiInstitute of Virology and AIDS Research, The First Hospital of Jilin University, Changchun, China.
Jilin University · CNFirst Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterovirus D68 (EV-D68) has emerged as a significant respiratory pathogen that can cause severe respiratory disease and acute neurologic disease. At present, there are no approved antiviral agents or vaccines for EV-D68. In this study, we demonstrate that andrographolide (ADO), an active component of

Indexed as

acidificationandrographolidedrug developmentendocytosisenterovirus D68

Identifiers

PMID30349523
PMCPMC6186950
OpenAlexW2897810838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.