Evidence map›Paper›PMID 30349464›Full record

ArticleFrontiers in behavioral neuroscience2018

Serotonin Mediates Depression of Aggression After Acute and Chronic Social Defeat Stress in a Model Insect.

Jan Rillich, Paul A Stevenson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

  1. The exploration of consciousness in insects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  2. Article
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  8. Pivotal mental states.Journal of psychopharmacology (Oxford, England) · 2021
    Review
  9. Review
  10. Article
  11. Role of Serotonin Transporter in Eye Development ofInternational journal of molecular sciences · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jan RillichInstitute for Biology, Leipzig University, Leipzig, Germany.
Paul A StevensonInstitute for Biology, Leipzig University, Leipzig, Germany.
Leipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all animals, losers of a conflict against a conspecific exhibit reduced aggressiveness, often coupled with depression-like symptoms, particularly after multiple defeats. While serotonin (5HT) is involved, discovering its natural role in aggression and depression has proven elusive. We show how 5HT influences aggression in male crickets, before, and after single and multiple defeats using serotonergic drugs, at dosages that had no obvious deleterious effect on general motility: the 5HT synthesis inhibitor alpha-methyltryptophan (AMTP), the 5HT

Indexed as

5HTaggressionagonistic behaviordopamineloser effectnitric oxideoctopaminesubjugation

Identifiers

PMID30349464
PMCPMC6186776
OpenAlexW2895903664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.