Evidence map›Paper›PMID 30349457›Full record

ArticleFrontiers in molecular neuroscience2018

Assessing Transcriptome Quality in Patch-Seq Datasets.

Shreejoy J Tripathy, Lilah Toker, Claire Bomkamp, B Ogan Mancarci, Manuel Belmadani, Paul Pavlidis

Abstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
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  3. Decoding Alzheimer's Disease One Cell Class at a Time.Cellular and molecular neurobiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shreejoy J TripathyMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
Lilah TokerMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
Claire BomkampDepartment of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
B Ogan MancarciMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
Manuel BelmadaniMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
Paul PavlidisMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.

Funding

Neuroinformatics for gene expression: networks, function and meta-analysisR01MH111099 · NIMH · UNIVERSITY OF BRITISH COLUMBIA · PI PAVLIDIS, PAUL · 2016 to 2025
$3.6M
NIMH NIH HHS R01 MH111099
6 · The paper itself

Abstract

Patch-seq, combining patch-clamp electrophysiology with single-cell RNA-sequencing (scRNAseq), enables unprecedented access to a neuron's transcriptomic, electrophysiological, and morphological features. Here, we present a re-analysis of five patch-seq datasets, representing cells from

Indexed as

cell typesgene expression profilingion channelsmeta-analysisneurophysiologypatch-clamp techniquessequencing data analysis

Identifiers

PMID30349457
PMCPMC6187980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.