Evidence map›Paper›PMID 30349362›Full record

ArticleCancer management and research2018

Clinical significance of prognostic score based on age, tumor size, and grade in gastric cancer after gastrectomy.

Jingfeng Lu, Yi Chen, Yanxia Liu, Junbin Ding, Zhenhao Piao, Weiyan Liu

Abstract read
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Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

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6citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jingfeng LuDepartment of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China, xiaolu201804@163.com; worldmanio@126.com.
Yi ChenDepartment of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China, xiaolu201804@163.com; worldmanio@126.com.
Yanxia LiuDepartment of Nursing, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China.
Junbin DingDepartment of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China, xiaolu201804@163.com; worldmanio@126.com.
Zhenhao PiaoDepartment of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China, xiaolu201804@163.com; worldmanio@126.com.
Weiyan LiuDepartment of General Surgery, Minhang Hospital, Fudan University, Minhang, Shanghai 201199, People's Republic of China, xiaolu201804@163.com; worldmanio@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative management and survival of gastric cancer is mainly determined by pathologic TNM stage. However, gastric cancer is a heterogeneity group, and the survival is quite different even when they are in the same TNM stage. Moreover, TNM stage system does not grasp other important clinicopathologic factors to determine the survival. The aim of the present study is to propose and validate prognostic score based on age, tumor size, and grade. MATERIALS AND

methodsPatients diagnosed with gastric cancer in the Surveillance, Epidemiology, and End Results database from 1988 to 2012 were included in the present study. Kaplan-Meier methods were adopted and multivariable Cox regression models were built for the analysis of long-term survival outcomes and risk factors.

resultsA total of 26,091 eligible patients diagnosed with noncardia gastric cancer were included in the study. In the univariate and multivariate survival analysis, age at diagnosis, tumor grade, and tumor size were validated as independent prognostic factors (

conclusionPrognostic score based on age, tumor size, and grade is an independent predictor of survival after gastrectomy. The novel prognostic score can improve the accuracy of prediction for current TNM stage system. Patients who are with a high prognostic score should undergo extensive follow-up after surgery.

Indexed as

gastric cancerprognostic scoresurvival analysis

Identifiers

PMID30349362
PMCPMC6183590

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.