Evidence map›Paper›PMID 30349334›Full record

ArticleInfection and drug resistance2018

Peptide dendrimers as "lead compounds" for the treatment of chronic lung infections by

Arianna Pompilio, Cristina Geminiani, Paolo Mantini, Thissa N Siriwardena, Ivan Di Bonaventura, Jean Louis Reymond, Giovanni Di Bonaventura

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Arianna PompilioDepartment of Medical, Oral, and Biotechnological Sciences, G d'Annunzio University of Chieti-Pescara, Chieti 66100, Italy, arianna.pompilio@unich.it.
Cristina GeminianiDepartment of Medical, Oral, and Biotechnological Sciences, G d'Annunzio University of Chieti-Pescara, Chieti 66100, Italy, arianna.pompilio@unich.it.
Paolo MantiniDepartment of Medical, Oral, and Biotechnological Sciences, G d'Annunzio University of Chieti-Pescara, Chieti 66100, Italy, arianna.pompilio@unich.it.
Thissa N SiriwardenaDepartment of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
Ivan Di BonaventuraDepartment of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
Jean Louis ReymondDepartment of Chemistry and Biochemistry, University of Bern, Bern, Switzerland.
Giovanni Di BonaventuraDepartment of Medical, Oral, and Biotechnological Sciences, G d'Annunzio University of Chieti-Pescara, Chieti 66100, Italy, arianna.pompilio@unich.it.
University of Chieti-Pescara · ITUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat

resultsThe activity of dendrimers against planktonic

conclusionOverall, our findings indicated that dG3KL and dTNS18 peptide dendrimers show in vitro activity comparable to Tob against both

Indexed as

biofilmchronic infectioncystic fibrosisdendrimer peptidesPseudomonas aeruginosa

Identifiers

PMID30349334
PMCPMC6188189
OpenAlexW2897562887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.