Evidence map›Paper›PMID 30349309›Full record

ArticleOncoTargets and therapy2018

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer.

Xue-Fang Du, Li-Li Zhang, De-Zhong Zhang, Lu Yang, Ying-Ying Fan, Shu-Ping Dong

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  8. Ginger (Antioxidants (Basel, Switzerland) · 2023
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  10. Polyphenols fromMolecules (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xue-Fang DuDepartment of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China, duxuefang880@126.com.
Li-Li ZhangDepartment of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China, duxuefang880@126.com.
De-Zhong ZhangGastrointestinal Surgery, The First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China.
Lu YangDepartment of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China, duxuefang880@126.com.
Ying-Ying FanDepartment of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China, duxuefang880@126.com.
Shu-Ping DongDepartment of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People's Republic of China, duxuefang880@126.com.
Xinxiang Medical University · CNFirst Affiliated Hospital of Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOxidative stress was significantly associated with the development of malignancies. The purpose of this study was to evaluate the significance of serum total oxidant/antioxidant status in operable advanced gastric cancer patients. MATERIALS AND

methodsA total of 284 patients who underwent curative resection for primary stage III gastric cancer were enrolled. Total oxidant status, total antioxidant status, and oxidative stress index (OSI) were evaluated within 24 hours before surgery, and compared with 120 healthy donors. The correlation between the OSI and survival outcome was analyzed by the Kaplan-Meier method with log-rank test and Cox's regression methods, respectively.

resultsMean OSI of gastric cancer patients was higher than healthy controls (1.41±0.96 vs 0.78±0.42,

conclusionPreoperative OSI can be considered as an independent prognostic factor for operable and advanced gastric cancer.

Indexed as

gastric canceroxidative stress indexsurvival

Identifiers

PMID30349309
PMCPMC6187998
OpenAlexW2896606972

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.