Evidence map›Paper›PMID 30349275›Full record

ArticleTherapeutics and clinical risk management2018

Evaluation of factors for poor outcome in preterm newborns with posthemorrhagic hydrocephalus associated with late-onset neonatal sepsis.

Marija Stevic, Dusica Simic, Nina Ristic, Ivana Budic, Vesna Marjanovic, Marija Jovanovski-Srceva, Nikola Repac, Milica Rankovic-Janevski, Goran Tasic

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Marija StevicDepartment of Anesthesia, Medical Faculty University of Belgrade, Belgrade, Serbia, mamarija74@gmail.com.
Dusica SimicDepartment of Anesthesia, Medical Faculty University of Belgrade, Belgrade, Serbia, mamarija74@gmail.com.
Nina RisticDepartment of Gastroenterology, University Children's Hospital, Belgrade, Serbia.
Ivana BudicDepartment of Anesthesia, Medical Faculty University of Nis, Nis, Serbia.
Vesna MarjanovicDepartment of Anesthesia, Medical Faculty University of Nis, Nis, Serbia.
Marija Jovanovski-SrcevaDepartment of Anesthesia, Medical Faculty University of Skopje, Skopje, Macedonia.
Nikola RepacClinical Center of Serbia, Institute of Neurosurgery, Belgrade, Serbia.
Milica Rankovic-JanevskiDepartment of the Specialized Care, Institute of Neonatology, Belgrade, Serbia.
Goran TasicClinical Center of Serbia, Institute of Neurosurgery, Belgrade, Serbia.
University of Belgrade · RSUniversity of Nis · RSCentar za Promociju Nauke · RSInstitute of Physics Belgrade · RSPHI University Psychiatric Clinic - Skopje · MKUniversity Children's Hospital, Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePreterm newborns, due to many factors, are at increased risk for poor neural development, intraventricular hemorrhages, infections, and higher rate of mortality. The aim of this study was to evaluate the risk factors associated with poor outcome in preterm neonates with late-onset neonatal sepsis (LONS) who had posthemorrhagic hydrocephalus and underwent neurosurgical procedures for treatment of the hydrocephalus. PATIENTS AND

methodsPreterm neonates who had undergone insertion of ventriculoperitoneal shunt or Ommaya reservoir, during the 10-year period at University Children's Hospital, were retrospectively analyzed. According to the presence or absence of LONS, patients were divided into LONS group and non-LONS group. In both groups, we analyzed demographic and clinical data as well as nondependent factors. Additionally, we evaluated the patients who had lethal outcome in respect to all the analyzed factors.

resultsA total of 74 patients were included in the study, 35 in LONS group and 39 in control group. Patients in LONS group were born significantly earlier with lower birth weight, needed significantly higher O

conclusionNeurosurgical procedures are relatively safe in neonates with posthemorrhagic hydrocephalus without LONS after birth. However, if LONS is present, various conditions such as preoperative high grade American Society of Anaesthesiologists score, ductus arteriosus persistens, bronchopulmonary dysplasia, and pneumothorax markedly increase the risk for a lethal outcome after the operation.

Indexed as

late-onset neonatal sepsismortalityposthemorrhagic hydrocephaluspreterm infantsrisk factors

Identifiers

PMID30349275
PMCPMC6188012
OpenAlexW2897845729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.