Evidence map›Paper›PMID 30349269›Full record

ArticleTherapeutics and clinical risk management2018

Predictors of new oral anticoagulant drug initiation as opposed to warfarin in elderly adults: a retrospective observational study in Southern Italy.

Francesca Guerriero, Valentina Orlando, Valeria Marina Monetti, Francesca Maria Colaccio, Maurizio Sessa, Cristina Scavone, Annalisa Capuano, Enrica Menditto

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Outcomes of Elderly Patients Undergoing Left Atrial Appendage Closure.Journal of the American Heart Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Francesca GuerrieroCenter of Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy, enrica.menditto@unina.it.
Valentina OrlandoCenter of Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy, enrica.menditto@unina.it.
Valeria Marina MonettiCenter of Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy, enrica.menditto@unina.it.
Francesca Maria ColaccioCaserta Local Health Unit, Caserta, Italy.
Maurizio SessaDepartment of Experimental Medicine, Section of Pharmacology, Regional Center of Pharmacovigilance, University of Campania "L. Vanvitelli", Naples, Italy.
Cristina ScavoneDepartment of Experimental Medicine, Section of Pharmacology, Regional Center of Pharmacovigilance, University of Campania "L. Vanvitelli", Naples, Italy.
Annalisa CapuanoDepartment of Experimental Medicine, Section of Pharmacology, Regional Center of Pharmacovigilance, University of Campania "L. Vanvitelli", Naples, Italy.
Enrica MendittoCenter of Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy, enrica.menditto@unina.it.
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to assess the predictive role of age, gender, and number and type of co-treatments for new oral anticoagulant (NOAC) vs warfarin prescription in elderly patients naïve for the aforementioned drugs. MATERIALS AND

methodsData collected in the period from January 1, 2014, to December 31, 2014, in Caserta Local Health Unit administrative databases (Campania Region, Italy) were screened to identify new users of oral anticoagulants (OACs) who were 75 years or older and whose OAC prescriptions amounted to >90 days of treatment. Age, gender, and number and type of concomitant medications at the time of first OAC dispensation were retrieved. Multivariable logistic regression analysis was used to assess the role of the aforementioned predictors for NOAC initiation as opposed to warfarin.

resultsOverall, 2,132 incident users of OAC were identified, of whom 967 met all inclusion criteria. In all, 490 subjects (50.7%) received an NOAC and 477 (49.3%) received warfarin. Age >75 years was positively associated with lower odds of NOAC initiation (OR: 0.969, 95% CI: 0.941-0.998,

conclusionAge and multiple co-medication were negatively associated with NOAC initiation.

Indexed as

atrial fibrillationdrug utilizationoral anticoagulationreal-world dataretrospective databases

Identifiers

PMID30349269
PMCPMC6183659
OpenAlexW2894799847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.