Evidence map›Paper›PMID 30349231›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Validation of ACCESS: an automated tool to support self-management of COPD exacerbations.

Lonneke M Boer, Maarten van der Heijden, Nathalie Me van Kuijk, Peter Jf Lucas, Jan H Vercoulen, Willem Jj Assendelft, Erik W Bischoff, Tjard R Schermer

Abstract readValidation Study
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Differentiating the start of an exacerbation from day-to-day variation in people with COPD: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effects of Adherence to an mHealth Tool for Self-Management of COPD Exacerbations.International journal of chronic obstructive pulmonary disease · 2023
    Article
  9. Mobile heath applications for self-management in chronic lung disease: a systematic review.Network modeling and analysis in health informatics and bioinformatics · 2023
    Review
  10. Article
  11. Article
  12. Observational
  13. eHealth for people with COPD in the Netherlands: a scoping review.International journal of chronic obstructive pulmonary disease · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lonneke M BoerDepartment of Primary and Community Care, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands, lonnekeboer@yahoo.co.uk.
Maarten van der HeijdenDepartment of Computing Sciences, Radboud University, Nijmegen, the Netherlands.
Nathalie Me van KuijkDepartment of Primary and Community Care, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands, lonnekeboer@yahoo.co.uk.
Peter Jf LucasDepartment of Computing Sciences, Radboud University, Nijmegen, the Netherlands.
Jan H VercoulenDepartment of Medical Psychology, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands.
Willem Jj AssendelftDepartment of Primary and Community Care, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands, lonnekeboer@yahoo.co.uk.
Erik W BischoffDepartment of Primary and Community Care, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands, lonnekeboer@yahoo.co.uk.
Tjard R SchermerDepartment of Primary and Community Care, Radboud university medical center, Radboud Institute for Health Sciences, Nijmegen, the Netherlands, lonnekeboer@yahoo.co.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo support patients with COPD in their self-management of symptom worsening, we developed Adaptive Computerized COPD Exacerbation Self-management Support (ACCESS), an innovative software application that provides automated treatment advice without the interference of a health care professional. Exacerbation detection is based on 12 symptom-related yes-or-no questions and the measurement of peripheral capillary oxygen saturation (SpO

methodsWe performed secondary analyses on data from a 3-month prospective observational study in which patients with COPD registered respiratory symptoms daily on diary cards and measured SpO

resultsFifty-four patients completed 2,928 diary cards. One or more of the different pieces of ACCESS advice were provided in 71.7% of all cases. We identified 115 symptom-based exacerbations. Cross-tabulation showed a sensitivity of 97.4% (95% CI 92.0-99.3), specificity of 65.6% (95% CI 63.5-67.6), and positive and negative predictive value of 13.4% (95% CI 11.2-15.9) and 99.8% (95% CI 99.3-99.9), respectively, for ACCESS' advice to contact a health care professional in case of an exacerbation.

conclusionIn many cases (71.7%), ACCESS gave at least one self-management advice to lower symptom burden, showing that ACCES provides self-management support for both day-to-day symptom variations and exacerbations. High sensitivity shows that if there is an exacerbation, ACCESS will advise patients to contact a health care professional. The high negative predictive value leads us to conclude that when ACCES does not provide the advice to contact a health care professional, the risk of an exacerbation is very low. Thus, ACCESS can safely be used in patients with COPD to support self-management in case of an exacerbation.

Indexed as

Pulmonary Disease, Chronic ObstructiveSelf-ManagementSoftwareSymptom Flare UpComputer-Assisted InstructionDecision Support TechniquesFemaleForced Expiratory VolumeHumansMaleMiddle AgedNetherlandsObservational Studies as TopicOximetryProgram EvaluationSymptom Assessmentautomated deviceCOPDdiagnostic accuracyexacerbationshealthmobile healthself-managementsoftware applicationtelehealthtreatment advice

Identifiers

PMID30349231
PMCPMC6188191

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.