ArticleInternational journal of chronic obstructive pulmonary disease
Increased serum levels of S100A1, ZAG, and adiponectin in cachectic patients with COPD.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- A review on clinical implications of S100 proteins in lung diseases.Frontiers in medicine · 2025Review
- Adiponectin as a predictor of mortality and readmission in patients with community-acquired pneumonia: a prospective cohort study.Frontiers in medicine · 2024Article
- Overexpression of S100A1 in Osteosarcoma Inhibits Tumor Proliferation and Progression.Iranian journal of public health · 2022Article
- Repurposing Multiple-Molecule Drugs for COVID-19-Associated Acute Respiratory Distress Syndrome and Non-Viral Acute Respiratory Distress Syndrome via a Systems Biology Approach and a DNN-DTI Model Based on Five Drug Design Specifications.International journal of molecular sciences · 2022Article
- Update on the Etiology, Assessment, and Management of COPD Cachexia: Considerations for the Clinician.International journal of chronic obstructive pulmonary disease · 2022Review
- Lipopolysaccharides induce a RAGE-mediated sensitization of sensory neurons and fluid hypersecretion in the upper airways.Scientific reports · 2021Article
- Clinical features of Japanese patients with exacerbations of chronic obstructive pulmonary disease.BMC pulmonary medicine · 2020Article
- Low FEV1 Is Associated With Increased Risk Of Cachexia In COPD Patients.International journal of chronic obstructive pulmonary disease · 2019Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOPD is a common irreversible obstructive airway disease. S100A1, ZAG, and adiponectin are important regulators of energy metabolism and body weight. Therefore, the aim of this study was to assess resting metabolic rate (RMR) and its association with serum levels of S100A1, ZAG, and adiponectin in cachectic and noncachectic COPD patients. PATIENTS AND
methodsNinety men with COPD, aged 40-70 years, were enrolled in the study. Patients were divided into the following two groups based on the unintentional weight loss of .7.5% in previous 6 months: noncachectic (n=45) and cachectic (n=45). The groups were matched based on age and body mass index (BMI). RMR was measured by indirect calorimetry method. Anthropometric indices and body composition were also measured. Serum levels of S100A1, ZAG, and adiponectin were measured by ELISA.
resultsCachectic patients had significantly higher RMR than controls (
conclusionThe potential role of these factors in the wasting process is considerable. Also, the association between serum levels of S100A1, ZAG, and adiponectin represents that these three proteins are probably related to specific functions.
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