ReviewPatient preference and adherence2018
Use of complementary and alternative medicine and adherence to antiepileptic drug therapy among epilepsy patients: a systematic review.
Review in Patient preference and adherence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- A prospective observational study evaluating drug-related problems and their impact on patient-related outcomes in hospitalized epileptic patients.Scientific reports · 2026Observational
- Epilepsy-Related Misconceptions, Cultural Beliefs, and Their Impact on Health Outcomes: A Systematic Review.Cureus · 2025Review
- Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia.Scientific reports · 2025Article
- Clinical Outcomes in Chronic Conditions: Findings from a Homeopathy Teaching Clinic using the MYCaW Instrument.Homeopathy : the journal of the Faculty of Homeopathy · 2024Article
- Complementary and Alternative Medicine for People with Epilepsy: Opinions of Physicians in Oman.Oman medical journal · 2024Article
- Complementary and alternative medicine use in migraine patients: results from a national patient e-survey.Frontiers in neurology · 2024Article
- Is there an Association between Complementary and Alternative Medicine use and Trust in Physicians in Patients with Rheumatic Diseases?Current rheumatology reviews · 2024Article
- Article
- Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry.Chinese medicine · 2022Review
- Effects of the COVID-19 pandemic on medication adherence: In the case of antiseizure medications, A scoping review.Seizure · 2021Article
- Treatment Adherence in Integrative Medicine-Part One: Review of Literature.Integrative medicine (Encinitas, Calif.) · 2021Review
- Medication adherence status among patients with neurological conditions and its association with quality of life.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Impact of complementary and alternative medicines on antiepileptic medication adherence among epilepsy patients.BMC complementary medicine and therapies · 2021Article
- Use of Adjuvant Endocrine Therapy Among Post-Menopausal Breast Cancer Patients in Malaysia.Patient preference and adherence · 2021Article
- Article
- Association of Child Neurology-Indian Epilepsy Society Consensus Document on Parental Counseling of Children with Epilepsy.Indian journal of pediatrics · 2019Review
- Molecular docking analysis of timepidium with Acetylcholine and lumacaftor with GABA(A) activator.Bioinformation · 2019Article
- Use of Complementary and Alternative Medicine and its Related Factors Among Pregnant Women in Shiraz, South of Iran: A Cross-Sectional Study.Iranian journal of nursing and midwifery researchArticle
- Attitudes Underlying Reliance on Complementary and Alternative Medicine.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo identify the use pattern of complementary and alternative medicine (CAM) and its impact on antiepileptic drug (AED) adherence among patients with epilepsy.
methodPotential studies were identified through a systematic search of Scopus, Science Direct, Google Scholar, and PubMed. The keywords used to identify relevant articles were "adherence," "AED," "epilepsy," "non-adherence," and "complementary and alternative medicine." An article was included in the review if the study met the following criteria: 1) conducted in epilepsy patients, 2) conducted in patients aged 18 years and above, 3) conducted in patients prescribed AEDs, and 4) patients' adherence to AEDs.
resultsA total of 3,330 studies were identified and 30 were included in the final analysis. The review found that the AED non-adherence rate reported in the studies was between 25% and 66%. The percentage of CAM use was found to be between 7.5% and 73.3%. The most common reason for inadequate AED therapy and higher dependence on CAM was the patients' belief that epilepsy had a spiritual or psychological cause, rather than primarily being a disease of the brain. Other factors for AED non-adherence were forgetfulness, specific beliefs about medications, depression, uncontrolled recent seizures, and frequent medication dosage.
conclusionThe review found a high prevalence of CAM use and non-adherence to AEDs among epilepsy patients. However, a limited number of studies have investigated the association between CAM usage and AED adherence. Future studies may wish to explore the influence of CAM use on AED medication adherence.
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