ArticleNature communications2018
Encoding of long-term associations through neural unitization in the human medial temporal lobe.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 50 citations in OpenAlex.
- Concept Cells and the Neural Bases of Human Memory.Acta physiologica (Oxford, England) · 2026Review
- Feature-based encoding of face identity by single neurons in the human amygdala and hippocampus.Nature human behaviour · 2025Article
- A neural computational framework for face processing in the human temporal lobe.Current biology : CB · 2025Article
- A neuronal code for object representation and memory in the human amygdala and hippocampus.Nature communications · 2025Article
- Lack of context modulation in human single neuron responses in the medial temporal lobe.Cell reports · 2025Article
- Integration of valence and conflict processing through cellular-field interactions in human subgenual cingulate during emotional face processing in treatment-resistant depression.Molecular psychiatry · 2025Article
- A preserved neural code for temporal order between memory formation and recall in the human medial temporal lobe.bioRxiv : the preprint server for biology · 2024Article
- A dynamic attractor network model of memory formation, reinforcement and forgetting.PLoS computational biology · 2023Article
- Single neuron responses underlying face recognition in the human midfusiform face-selective cortex.Nature communications · 2023Article
- Using multi-task experiments to test principles of hippocampal function.Hippocampus · 2023Article
- Single-neuron mechanisms of neural adaptation in the human temporal lobe.Nature communications · 2023Article
- Purely STDP-based assembly dynamics: Stability, learning, overlaps, drift and aging.PLoS computational biology · 2023Article
- Model Sharing in the Human Medial Temporal Lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Face identity coding in the deep neural network and primate brain.Communications biology · 2022Article
- Brain activity patterns underlying memory confidence.The European journal of neuroscience · 2022Review
- An Event-Related Potential Study on Differences Between Higher and Lower Easy of Learning Judgments: Evidence for the Ease-of-Processing Hypothesis.Frontiers in psychology · 2022Article
- When shared concept cells support associations: Theory of overlapping memory engrams.PLoS computational biology · 2021Article
- Concept neurons in the human medial temporal lobe flexibly represent abstract relations between concepts.Nature communications · 2021Article
- Concept formation as a computational cognitive process.Current opinion in behavioral sciences · 2021Article
- The Architecture of Human Memory: Insights from Human Single-Neuron Recordings.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Besides decades of research showing the role of the medial temporal lobe (MTL) in memory and the encoding of associations, the neural substrates underlying these functions remain unknown. We identified single neurons in the human MTL that responded to multiple and, in most cases, associated stimuli. We observed that most of these neurons exhibit no differences in their spike and local field potential (LFP) activity associated with the individual response-eliciting stimuli. In addition, LFP responses in the theta band preceded single neuron responses by ~70 ms, with the single trial phase providing fine tuning of the spike response onset. We postulate that the finding of similar neuronal responses to associated items provides a simple and flexible way of encoding memories in the human MTL, increasing the effective capacity for memory storage and successful retrieval.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.