ArticleNature communications2018
Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells.
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In one paragraph
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed.
- A guide to B cell metabolism.Nature reviews. Immunology · 2026Review
- Metabolic determinants of autoimmune kidney diseases.Nature reviews. Nephrology · 2026Review
- A targeted metabolic intervention via exercise applied after vaccination shapes kinetics and durability of serum antibody accompanied by a distinct immunometabolic signature: pilot study.Brain, behavior, & immunity - health · 2026Article
- Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026Review
- GLUT1-mediated glucose flux constrains autoreactive but not foreign antigen-specific B-cell responses.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Multiomics-guided discovery of protective microbiome signatures in lupus-prone mice treated with Faecalibacterium prausnitzii.Nature communications · 2026Article
- Glucose metabolic reprogramming in systemic lupus erythematosus and lupus nephritis: theoretical foundations and therapeutic implications.Frontiers in immunology · 2026Review
- Integrating T cell signaling and metabolism to enhance T cell engager responses in solid tumors.Frontiers in immunology · 2026Review
- Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus.Cell reports · 2025Article
- Article
- Metabolic pathways within cTfh subsets and glucose-dependent activation of cTfh17 in SLE and healthy individuals.JCI insight · 2025Article
- Immunometabolism in systemic lupus erythematosus.Nature reviews. Rheumatology · 2025Review
- Gut Expansion of a Human Lupus Pathobiont is Associated With Autoantibody Production and T Cell Dysregulation.ACR open rheumatology · 2025Article
- The impact of metabolic reprogramming on tertiary lymphoid structure formation: enhancing cancer immunotherapy.BMC medicine · 2025Review
- The Possible Role of Metformin and Fibroblast Growth Factor-21 in Multiple Sclerosis Neuropathology: Birds of a Feather Flock Together.The European journal of neuroscience · 2025Review
- Sweet regulation - The emerging immunoregulatory roles of hexoses.Journal of advanced research · 2025Review
- Nervous system-gut microbiota-immune system axis: future directions for preventing tumor.Frontiers in immunology · 2025Review
- Exploring the differential functions of circulating follicular helper T and peripheral helper T cells in rheumatoid arthritis based on metabolism patterns.Frontiers in immunology · 2025Article
- PI3K-dependent reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes.iScience · 2024Article
- Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus.Amino acids · 2024Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Seung-Chul ChoiDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0001-6230-9087
Anton A TitovDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0003-2751-2340
Georges AbboudDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.
Howard R SeayDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0001-7002-0187
Todd M BruskoDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.ORCID http://orcid.org/0000-0003-2878-9296
Derry C RoopenianThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, 04609, USA.
Shahram Salek-ArdakaniDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA.
Laurence MorelDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida, 1395 Center Drive, Gainesville, FL, 32610, USA. morel@ufl.edu.
Funding
Project 3P01AI042288 · NIAID · UNIVERSITY OF FLORIDA · PI Todd Michael Brusko · 1997 to 2026
$32.9MCharacterization of SLE-susceptibility loci on mouse chromosome 1R01AI045050 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Laurence Morel · 2000 to 2026
$11.5MTargeting follicular helper CD4 T cells in SLER01AI128901 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2017 to 2021
$1.8MAlliance for Lupus Research (ALR) TIL-416522NIAID NIH HHS P01 AI042288NIAID NIH HHS R01 AI045050NIAID NIH HHS R01 AI128901
Abstract
Follicular helper T (T
Indexed as
Amino AcidsAnimalsAutoantibodiesAutoimmunityEnzyme-Linked Immunosorbent AssayFemaleFlow CytometryGlucoseLupus Erythematosus, SystemicMiceT-Lymphocytes, Helper-InducerAmino AcidsAutoantibodiesGlucose
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.