Evidence map›Paper›PMID 30348967›Full record

ArticleBlood cancer journal2018

CD26 is a potential therapeutic target by humanized monoclonal antibody for the treatment of multiple myeloma.

Hiroko Nishida, Mutsumi Hayashi, Chikao Morimoto, Michiie Sakamoto, Taketo Yamada

Open access · goldAbstract read
In one paragraph

Article in Blood cancer journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hiroko NishidaDepartment of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Mutsumi HayashiDepartment of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Chikao MorimotoDepartment of Therapy Development and Innovation for Immune Disorders and Cancers, Graduate School of Medicine, Juntendo University, Bunkyo-ku, Tokyo, Japan.
Michiie SakamotoDepartment of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Taketo YamadaDepartment of Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. taketo@saitama-med.ac.jp.
Keio University · JPJuntendo University · JPSaitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD26, a 110-kDa transmembrane glycoprotein that is expressed on several tumor cells including malignant lymphoma, has been implicated in tumorigenesis: however, little is known regarding its role in multiple myeloma (MM). Recently, we identified CD26 expression on human osteoclasts (OCs) and demonstrated that humanized IgG

Indexed as

AnimalsAntibodies, Monoclonal, HumanizedAntibody-Dependent Cell CytotoxicityAntineoplastic Agents, ImmunologicalBone MarrowCell AdhesionCell Line, TumorCell SurvivalComplement System ProteinsDipeptidyl Peptidase 4Disease Models, AnimalFemaleHumansMiceMultiple MyelomaPlasma CellsAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalComplement System ProteinsDipeptidyl Peptidase 4DPP4 protein, human

Identifiers

PMID30348967
PMCPMC6197267
OpenAlexW2897527444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.