Evidence map›Paper›PMID 30348901›Full record

ArticleThe Journal of biological chemistry2018

Phosphatidylinositol 4,5-bisphosphate (PIP

Frank S Choveau, Victor De la Rosa, Sonya M Bierbower, Ciria C Hernandez, Mark S Shapiro

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Coupling of functionality to trafficking of KCNQ2/3 potassium channels at the axon initial segment.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. CaNature communications · 2025
    Article
  4. Article
  5. Review
  6. Involvement of CaCellular and molecular neurobiology · 2023
    Article
  7. Modulation of the IBBA advances · 2023
    Article
  8. Triclosan is a KCNQ3 potassium channel activator.Pflugers Archiv : European journal of physiology · 2022
    Article
  9. Article
  10. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity.International journal of molecular sciences · 2022
    Article
  11. Article
  12. PIPCommunications biology · 2021
    Article
  13. Article
  14. Kv7 Channels and Excitability Disorders.Handbook of experimental pharmacology · 2021
    Article
  15. Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation.International journal of molecular sciences · 2020
    Review
  16. Article
  17. A PIPCommunications biology · 2020
    Article
  18. Article
  19. Atomistic Insights of Calmodulin Gating of Complete Ion Channels.International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Frank S ChoveauFrom the Department of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Victor De la RosaFrom the Department of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Sonya M BierbowerFrom the Department of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229.
Ciria C Hernandezthe Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, and ciria@umich.edu.
Mark S ShapiroFrom the Department of Cell and Integrative Physiology, University of Texas Health San Antonio, San Antonio, Texas 78229, shapirom@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · USVanderbilt University Medical Center · US

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
PATHOBIOLOGY OF OCCLUSIVE VASCULAR DISEASET32HL007446 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Jean Chrisostome Bopassa · 1985 to 2026
$8.9M
Modulation of Neuronal Ion Channels by 2nd MessengersR01NS043394 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2002 to 2014
$4.5M
Targeting specific interactions between A-kinase Anchoring Proteins (AKAPs) and ion channels with cell-permeant peptides as a novel mode of therapeutic intervention against pain disordersR01NS094461 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2015 to 2019
$2.0M
Mechanism and functional role of AKAP79/150 in M current control and excitabilityR01NS065138 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2009 to 2010
$788k
NCATS NIH HHS UL1 TR001120NHLBI NIH HHS T32 HL007446NINDS NIH HHS R01 NS043394NINDS NIH HHS R01 NS065138NINDS NIH HHS R01 NS094461
6 · The paper itself

Abstract

Phosphatidylinositol 4,5-bisphosphate (PIP

Indexed as

Amino Acid SequenceAnimalsCHO CellsCricetulusCytoplasmHumansKCNQ3 Potassium ChannelModels, MolecularMutationPhosphatidylinositol 4,5-DiphosphateProtein BindingProtein Conformation, alpha-HelicalProtein DomainsKCNQ3 Potassium ChannelPhosphatidylinositol 4,5-Diphosphateion channel gatingion channel modulationKCNQlipid signalingM currentneurosciencephospholipidPIP2potassium channelsignal transductionstructure-function

Identifiers

PMID30348901
PMCPMC6302169
OpenAlexW2896703752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.