Evidence map›Paper›PMID 30348806›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Nonequilibrium associative retrieval of multiple stored self-assembly targets.

Gili Bisker, Jeremy L England

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Identification and quantification of irreversibility in stochastic systems.Physical chemistry chemical physics : PCCP · 2026
    Review
  2. Article
  3. Coarse-Graining Self-Assembly by the Stochastic Landscape Method.Journal of chemical theory and computation · 2025
    Article
  4. Nonequilibrium Self-Assembly Control by the Stochastic Landscape Method.Journal of chemical information and modeling · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Temperature protocols to guide selective self-assembly of competing structures.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Lessons from equilibrium statistical physics regarding the assembly of protein complexes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gili BiskerPhysics of Living Systems Group, Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0003-2592-7956
Jeremy L EnglandPhysics of Living Systems Group, Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139; jengland@mit.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many biological systems rely on the ability to self-assemble different target structures using the same set of components. Equilibrium self-assembly suffers from a limited capacity in such cases, due to an increasing number of decoy states that grows rapidly with the number of targets encoded. Moreover, improving the kinetic stability of a target at equilibrium carries the price of introducing kinetic traps, leading to slower assembly. Using a toy physical model of interacting particles, we demonstrate that local driving can improve both the assembly time and kinetic stability of multitarget self-assembly, as well as reduce fluctuations around the target configuration. We further show that the local drive can result in a steady-state probability distribution over target structures that deviates from the Boltzmann distribution in a way that depends on the types of interactions that stabilize the targets. Our results illustrate the role that nonequilibrium driving plays in overcoming tradeoffs that are inherent to equilibrium assemblies.

Indexed as

local drivingnonequilibrium self-assemblyself-healingstored structures

Identifiers

PMID30348806
PMCPMC6233095

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.