ArticleProceedings of the National Academy of Sciences of the United States of America2018
Dopamine D2 receptor-mediated circuit from the central amygdala to the bed nucleus of the stria terminalis regulates impulsive behavior.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.JAMA psychiatry · 2023Pooled it
- Effects of the monoamine stabilizer (-)OSU6162 on cognitive function in alcohol dependence.Psychopharmacology · 2020Trial
- mGluR5 in ECAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transsynaptic neural circuit mapping of ventral hippocampus motivational control systems.Brain structure & function · 2026Article
- Contributions of the interaction between mu-opioid receptors and dopamine receptors in the regulation of risky decision making.Progress in neuro-psychopharmacology & biological psychiatry · 2026Article
- Social processing in the amygdala: single-nucleus RNA-sequencing reveals distinct neuronal responses to dominant and subordinate cues.Scientific reports · 2026Article
- Central amygdala neuropeptide Y neurons drive hedonic ingestive behaviour independent of energy homeostasis.International journal of obesity (2005) · 2026Article
- Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder.BMC medicine · 2026Article
- Social Processing in the Amygdala: Single-Nucleus RNA-Sequencing Reveals Distinct Neuronal Responses to Dominant and Subordinate Cues.Research square · 2026Article
- Dopamine D2 receptor modulation of insulin receptor signaling in the central amygdala: implications for compulsive-like eating behavior.Molecular psychiatry · 2026Article
- Aberrant striatal firing mediates impulsive decision-making in a mouse model of Parkinson's disease.Brain : a journal of neurology · 2026Article
- Social Processing in the Amygdala: Single-Nucleus RNA-Sequencing Reveals Distinct Neuronal Responses to Dominant and Subordinate Cues.bioRxiv : the preprint server for biology · 2025Article
- Review
- Optogenetic Control of Dopamine Receptor 2 Reveals a Novel Aspect of Dopaminergic Neurotransmission in Motor Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Dopamine D2 receptors in the bed nucleus of the stria terminalis modulate alcohol-related behaviors.Addiction neuroscience · 2024Article
- Accentuated Paralimbic and Reduced Mesolimbic DThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Pharmacological Modulation of Temporal Discounting: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Early life exposure to high fructose diet induces metabolic dysregulation associated with sex-specific cognitive impairment in adolescent rats.The Journal of nutritional biochemistry · 2023Article
- Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically segregated regions.Brain structure & function · 2023Article
- Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Impulsivity is closely associated with addictive disorders, and changes in the brain dopamine system have been proposed to affect impulse control in reward-related behaviors. However, the central neural pathways through which the dopamine system controls impulsive behavior are still unclear. We found that the absence of the D2 dopamine receptor (D2R) increased impulsive behavior in mice, whereas restoration of D2R expression specifically in the central amygdala (CeA) of D2R knockout mice (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.