Evidence map›Paper›PMID 30348661›Full record

ArticleAntimicrobial agents and chemotherapy2019

Promising New Antifungal Treatment Targeting Chorismate Synthase from

Franciele Abigail Vilugron Rodrigues-Vendramini, Cidnei Marschalk, Marina Toplak, Peter Macheroux, Patricia de Souza Bonfim-Mendonça, Terezinha Inez Estivalet Svidzinski, Flavio Augusto Vicente Seixas, Erika Seki Kioshima

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Investigation of the inhibitory properties of azo-dyes on chorismate synthase fromJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. One Century of Study: What We Learned aboutJournal of fungi (Basel, Switzerland) · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Living Within the Macrophage: Dimorphic Fungal Pathogen Intracellular Metabolism.Frontiers in cellular and infection microbiology · 2020
    Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Franciele Abigail Vilugron Rodrigues-VendraminiDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Cidnei MarschalkDepartment of Technology, Universidade Estadual de Maringá, Umuarama, Paraná, Brazil.
Marina ToplakInstitute for Biochemistry, Graz University of Technology, Graz, Austria.
Peter MacherouxInstitute for Biochemistry, Graz University of Technology, Graz, Austria.
Patricia de Souza Bonfim-MendonçaDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Terezinha Inez Estivalet SvidzinskiDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Maringá, Paraná, Brazil.
Flavio Augusto Vicente SeixasDepartment of Technology, Universidade Estadual de Maringá, Umuarama, Paraná, Brazil.
Erika Seki KioshimaDepartment of Clinical Analysis and Biomedicine, Universidade Estadual de Maringá, Maringá, Paraná, Brazil eskioshima@gmail.com.
Universidade Estadual de Maringá · BRGraz University of Technology · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracoccidioidomycosis (PCM), caused by

Indexed as

Amino Acid SequenceAnimalsAntifungal AgentsCell Line, TumorDisease Models, AnimalDrug DiscoveryHeLa CellsHumansHuman Umbilical Vein Endothelial CellsItraconazoleMaleMiceMice, Inbred BALB CMicrobial Sensitivity TestsMicroscopy, Electron, ScanningMolecular Dynamics SimulationAntifungal Agentschorismate synthaseItraconazolePhosphorus-Oxygen LyasesQuinolineschorismate synthasemolecular modelingnew antifungalparacoccidioidomycosisvirtual screening

Identifiers

PMID30348661
PMCPMC6325199
OpenAlexW2896072016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.