Evidence map›Paper›PMID 30348651›Full record

ArticleGenetics2018

Incompatibilities in Mismatch Repair Genes

Vandana Raghavan, Duyen T Bui, Najla Al-Sweel, Anne Friedrich, Joseph Schacherer, Charles F Aquadro, Eric Alani

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  8. SUMO and cellular adaptive mechanisms.Experimental & molecular medicine · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vandana RaghavanDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Duyen T BuiDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.ORCID 0000-0003-4231-0587
Najla Al-SweelDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Anne FriedrichUniversité de Strasbourg, Centre National de la Recherche Scientifique, Laboratory of Molecular Genetics, Genomics and Microbiology (GMGM) UMR 7156, F-67000, France.
Joseph SchachererUniversité de Strasbourg, Centre National de la Recherche Scientifique, Laboratory of Molecular Genetics, Genomics and Microbiology (GMGM) UMR 7156, F-67000, France.
Charles F AquadroDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703.
Eric AlaniDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853-2703 eea3@cornell.edu.ORCID 0000-0002-5011-9339
Cornell University · USUniversité de Strasbourg · FR

Funding

Roles for Mismatch Repair Proteins in Maintaining Genome StabilityR01GM053085 · NIGMS · CORNELL UNIVERSITY ITHACA · PI ALANI, ERIC E. · 1995 to 2019
$7.3M
Adaptive Protein Evolution of the Drosophila Germline Stem Cell Gene Bag of MarblesR01GM095793 · NIGMS · CORNELL UNIVERSITY · PI AQUADRO, CHARLES F · 2011 to 2024
$3.9M
Roles for Mismatch Repair Proteins in Maintaining Genome StabilityR35GM134872 · NIGMS · CORNELL UNIVERSITY · PI Eric E. Alani · 2020 to 2026
$2.8M
NIGMS NIH HHS R01 GM053085NIGMS NIH HHS R01 GM095793NIGMS NIH HHS R35 GM134872
6 · The paper itself

Abstract

Laboratory baker's yeast strains bearing an incompatible combination of

Indexed as

AllelesDNA Mismatch RepairDNA RepairGenotypeHumansMutationMutation RateMutL Protein Homolog 1MutL ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSelection, GeneticSpores, FungalMLH1 protein, S cerevisiaeMutL Protein Homolog 1MutL ProteinsPMS1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsadaptationDNA mismatch repairgenetic incompatibilitymutation ratenatural yeast isolatesSaccharomyces cerevisiae

Identifiers

PMID30348651
PMCPMC6283166
OpenAlexW2897430193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.