ArticleBrazilian journal of anesthesiology (Elsevier)
[Severe bradycardia and asystole associated with sugammadex: case report].
Article in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Sudden, Severe, Refractory Hypotension Following Sugammadex Administration During Low-Risk Orthopedic Surgery in a Healthy Young Adult: A Case Report.Case reports in anesthesiology · 2026Article
- Asystolic cardiac arrest secondary to sugammadex administration in a young patient.Anaesthesiology intensive therapy · 2024Article
- Severe Hypotension, Bradycardia and Asystole after Sugammadex Administration in an Elderly Patient.Medicina (Kaunas, Lithuania) · 2021Article
- Should we Routinely Reverse Neuromuscular Blockade with Sugammadex in Patients with a History of Heart Transplantation?Translational perioperative and pain medicine · 2020Article
- Sugammadex-Associated Hypotension, Bradycardia, Asystole, and Death.Case reports in anesthesiology · 2020Article
- Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient.Case reports in anesthesiology · 2019Article
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6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesSugamadex is a modified gamma-cyclodextrin, the first selective agent for reversal of neuromuscular blockade induced by steroidal non-depolarizing muscle relaxants, with greater affinity for rocuronium. In this article we present a case of severe bradycardia and asystole following sugammadex administration. CASE REPORT: A 54-year-old male patient, ASA II, with a history of hypertension, dyslipidemia and obesity, who underwent an emergency umbilical herniorrhaphy under balanced general anesthesia. Intraoperative muscle relaxation was maintained with rocuronium. At the end of the surgery, the patient maintained a neuromuscular block with two TOF responses, and sugammadex (200mg) was administered. About thirty seconds after its administration, the patient developed marked bradycardia (HR 30 bpm) followed by asystole.
conclusionsDocumented bradycardia and asystole were attributed to the administration of sugammadex. This case shows that, although rare, cardiac arrest is a possible adverse effect of this drug, and that the knowledge of this situation can be determinant for the patient's evolution.
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