Evidence map›Paper›PMID 30348198›Full record

Trial reportBMC research notes2018

Visual biofeedback training reduces quantitative drugs index scores associated with fall risk.

Eric Anson, Elizabeth Thompson, Samuel C Karpen, Brian L Odle, Edith Seier, John Jeka, Peter C Panus

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Eric AnsonDepartment of Otolaryngology, University of Rochester, 601 Elmwood Avenue, Box 629, Rochester, NY, 14642, USA.
Elizabeth ThompsonDepartment of Physical Therapy, Temple University, 1800 N Broad St, Philadelphia, PA, 91222, USA.
Samuel C KarpenUniversity of Georgia College of Veterinary Medicine, 501 D. W. Brooks Drive, Athens, GA, 30602, USA.
Brian L OdlePharmacy Practice, Gatton College of Pharmacy, East Tennessee State University, Box 70594, Johnson City, TN, 37614, USA.
Edith SeierMathematics and Statistics Department, College of Arts and Sciences, East Tennessee State University, Box 70663, Johnson City, TN, 37614, USA.
John JekaDepartment of Kinesiology and Applied Physiology, University of Delaware, STAR Health Sciences Campus, 540 S College Ave, Newark, DE, 19713, USA.
Peter C PanusPharmaceutical Sciences, Gatton College of Pharmacy, East Tennessee State University, Box 70657, Johnson City, TN, 37614, USA. panus@etsu.edu.ORCID http://orcid.org/0000-0001-7520-0662
East Tennessee State University · USGeorgia College & State University · USTemple University · USUniversity of Delaware · USUniversity of Rochester · US

Funding

Training Program in Hearing and BalanceT32DC000023 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CULLEN, KATHLEEN E · 1989 to 2025
$8.7M
Sensory Treadmill to Improve of Balance During WalkingR21AG041714 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI JEKA, JOHN JOSEPH · 2012 to 2013
$378k
Foundation for Physical Therapy II ScholarshipsFoundation for Physical Therapy Promotion of Doctoral Studies INational Institutes of Health 7R21AG041714National Institutes of Health NIDCD T32 DC000023NIA NIH HHS R21 AG041714NIDCD NIH HHS T32 DC000023
6 · The paper itself

Abstract

objectiveDrugs increase fall risk and decrease performance on balance and mobility tests. Conversely, whether biofeedback training to reduce fall risk also decreases scores on a published drug-based fall risk index has not been documented. Forty-eight community-dwelling older adults underwent either treadmill gait training plus visual feedback (+VFB), or walked on a treadmill without feedback. The Quantitative Drug Index (QDI) was derived from each participant's drug list and is based upon all cause drug-associated fall risk. Analysis of covariance assessed changes in the QDI during the study, and data is presented as mean ± standard error of the mean.

resultsThe QDI scores decreased significantly (p = 0.031) for participants receiving treadmill gait training +VFB (- 0.259 ± 0.207), compared to participants who walked on the treadmill without VFB (0.463 ± 0.246). Changes in participants QDI scores were dependent in part upon their age, which was a significant covariate (p = 0.007). These preliminary results demonstrate that rehabilitation to reduce fall risk may also decrease use of drugs associated with falls. Determination of which drugs or drug classes that contribute to the reduction in QDI scores for participants receiving treadmill gait training +VFB, compared to treadmill walking only, will require a larger participant investigation. Trial Registration ISRNCT01690611, ClinicalTrials.gov #366151-1, initial 9/24/2012, completed 4/21/2016.

Indexed as

Accidental FallsAgedAged, 80 and overBiofeedback, PsychologyCombined Modality TherapyDrug-Related Side Effects and Adverse ReactionsExercise TherapyHumansTreatment OutcomeAmbulatoryBiofeedbackCommunityCovariateDrug indexElderlyFallsPolypharmacyTreadmillVisual

Identifiers

PMID30348198
PMCPMC6196457
OpenAlexW2897656788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.