SynthesisJournal of orthopaedic surgery and research2018
Balloon kyphoplasty versus percutaneous vertebroplasty for osteoporotic vertebral compression fracture: a meta-analysis and systematic review.
Synthesis in Journal of orthopaedic surgery and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07024095 ("Effects of Inspiratory Muscle Training on Pulmonary Function, Functional Capacity, and Quality of Life After Percutaneous Vertebroplasty in Individuals With Osteoporotic Vertebral Compression Fracture"), which is not on this map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
"Effects of Inspiratory Muscle Training on Pulmonary Function, Functional Capacity, and Quality of Life After Percutaneous Vertebroplasty in Individuals With Osteoporotic Vertebral Compression Fracture"
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Efficacy and safety of vertebroplasty versus posterior pedicle screw in treating stage III Kummell's disease without neurological deficits: A systematic review and meta-analysis.The Journal of international medical research · 2025Pooled it
- Re-evaluating vertebral height restoration assessment in osteoporotic compression fractures: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Unilaterally extrapedicular versus transpedicular kyphoplasty in treating osteoporotic lumbar fractures: a randomized controlled study.Journal of orthopaedic surgery and research · 2023Trial
- Per-Vertebra Prediction of Future Osteoporotic Fractures from Routine Computed Tomography Using a Two-Stage Machine Learning Framework.Medicina (Kaunas, Lithuania) · 2026Article
- Osteoporosis: The Renascent Impact of Vertebral Fractures-A Narrative Review of Diagnosis, Risk Stratification, and Integrated Management.Journal of clinical medicine · 2026Review
- Health-related Quality of Life After Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures.Current osteoporosis reports · 2026Review
- Reduced walking speed at discharge predicts mortality after clinical osteoporotic vertebral fracture: A retrospective cohort study.Archives of osteoporosis · 2026Article
- Outcomes of revision vertebral augmentation for recurrent or adjacent osteoporotic vertebral compression fractures: a systematic review and meta-analysis.Orthopedic reviews · 2026Article
- Current Evidence and Clinical Implications of Full-Endoscopic Spine Surgery for Post-Vertebroplasty Lumbar Radiculopathy: A Comprehensive Review.Journal of pain research · 2026Review
- Small intestinal necrosis caused by the embolism of the superior mesenteric artery after percutaneous vertebroplasty: a case report and analysis of the causes.BMC musculoskeletal disorders · 2025Article
- Answer to the letter to the editor of CZ Liu, et al. concerning "Association between vertebral bone quality score and residual back pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures" by Chen C, et al. (Eur Spine J [2024]: doi: 10.1007/s00586-024-08619-6).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Clinical efficacy analysis of extrapedicular unilateral percutaneous vertebroplasty via the upper edge of the transverse process for lumbar osteoporotic vertebral compression fractures.BMC musculoskeletal disorders · 2025Article
- Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis.Asian spine journal · 2025Article
- Establishment of a risk prediction model for residual back pain after percutaneous kyphoplasty in osteoporotic vertebral compression fractures.Frontiers in surgery · 2025Article
- Global Research Trends and Hotspots on Percutaneous Kyphoplasty and Osteoporotic Vertebral Body Compression Fractures: A Bibliometric Analysis.Journal of multidisciplinary healthcare · 2025Article
- Percutaneous Vertebroplasty Using GeneXInternational medical case reports journal · 2025Article
- Efficiency and Safety of Repeated Vertebroplasty for Adjacent Segment Fractures.Journal of clinical medicine · 2024Article
- Percutaneous Vesselplasty for the Treatment of Vertebral Osteoporotic Collapse Fractures.Cureus · 2024Article
- Comparison of the efficacy and safety of vertebroplasty with different pedicle approaches for osteoporotic vertebral.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Review
- Rheological Analysis and Evaluation of Measurement Techniques for Curing Poly(Methyl Methacrylate) Bone Cement in Vertebroplasty.ACS biomaterials science & engineering · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis meta-analysis was aimed to explore the overall safety and efficacy of balloon kyphoplasty versus percutaneous vertebroplasty for osteoporotic vertebral compression fracture (OVCF) based on qualified studies.
methodsBy searching multiple databases and sources, including PubMed, Cochrane, and Embase by the index words updated to January 2018, qualified studies were identified and relevant literature sources were also searched. The qualified studies included randomized controlled trials, prospective or retrospective comparative studies, and cohort studies. The meta-analysis was performed including mean difference (MD) or relative risk (RR) and 95% confidence interval (95% CI) to analyze the main outcomes.
resultsA total of 16 studies were included in the meta-analysis to explore the safety and efficacy of kyphoplasty versus vertebroplasty for the treatment of OVCF. The results indicated that kyphoplasty significantly decreased the kyphotic wedge angle (SMD, 0.98; 95% CI 0.40-1.57), increased the postoperative vertebral body height (SMD, - 1.27; 95% CI - 1.86 to - 0.67), and decreased the risk of cement leakage (RR, 0.62; 95% CI 0.47-0.80) in comparison with vertebroplasty. However, there was no statistical difference in visual analog scale (VAS) scores (WMD, 0.04; 95% CI - 0.28-0.36) and Oswestry Disability Index (ODI) scores (WMD, - 1.30; 95% CI - 3.34-0.74) between the two groups.
conclusionsKyphoplasty contributes especially to decreasing the mean difference of kyphotic wedge angle and risk of cement leakage and increasing the vertebral body height when compared with vertebroplasty. But radiographic differences did not significantly influence the clinical results (no significant difference was observed in VAS scores and ODI scores between the two groups); thus, kyphoplasty and vertebroplasty are equally effective in the clinical outcomes of OVCF. In addition, more high-quality multi-center RCTs with a larger sample size and longer follow-up are warranted to confirm the current findings.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.