SynthesisBMC nephrology2018
Incidence and impact on outcomes of acute kidney injury after a stroke: a systematic review and meta-analysis.
Synthesis in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prediction Models for Acute Kidney Injury in Stroke Patients: A Systematic Review.Brain and behavior · 2026Pooled it
- Impact on mortality at 90 days of acute kidney injuries in endovascularly treated stroke: A systematic review, meta-analysis, and meta-regression.The neuroradiology journal · 2025Pooled it
- Acute kidney injury after a stroke: A PRISMA-compliant meta-analysis.Brain and behavior · 2020Pooled it
- A Study of Acute Kidney Injury in Stroke Patients and Its Relationship to Short-term Outcome.Annals of African medicine · 2026Observational
- Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre-Existing Renal Impairment.Annals of clinical and translational neurology · 2026Article
- An online dynamic nomogram for predicting acute kidney injury after endovascular therapy in acute ischemic stroke.BMC nephrology · 2026Article
- Case Report: Neurogenic pulmonary edema coupled with myocardial damage following tenecteplase thrombolysis for acute ischemic stroke.Frontiers in cardiovascular medicine · 2026Article
- Article
- Predictive value of neutrophil-to-albumin ratio for the incidence of acute kidney injury in intracerebral hemorrhage patients.Neurosurgical review · 2025Article
- Mortality Risk Analysis of Combination Antiplatelet Therapy in Patients with Ischemic Stroke and Acute Kidney Injury: A Retrospective Cohort Analysis of the MIMIC-IV Database.Diseases (Basel, Switzerland) · 2025Article
- Prognostic Impact of 1-Year Changes in Creatinine- and Cystatin C-Based Estimated Glomerular Filtration Rate After Stroke on 5-Year Outcomes: Insights From the Third China National Stroke Registry.Journal of the American Heart Association · 2025Article
- Vitamin D deficiency and risk of acute kidney injury after ischemic stroke: a propensity-matched cohort study.Frontiers in nutrition · 2025Article
- Impact of Acute Kidney Injury, Co-Existing with and without Chronic Kidney Disease on the Short-Term Adverse Outcomes Following Atherosclerotic Cardiovascular Disease Events in Patients with Diabetes.Journal of multidisciplinary healthcare · 2025Article
- Stroke-Induced Renal Dysfunction: Underlying Mechanisms and Challenges of the Brain-Kidney Axis.CNS neuroscience & therapeutics · 2024Review
- Article
- Article
- Machine learning for the prediction of acute kidney injury in critical care patients with acute cerebrovascular disease.Renal failure · 2022Article
- Contrast-Associated Acute Kidney Injury After Endovascular Therapy for Acute Ischemic Stroke: A Meta-Analysis.Stroke (Hoboken, N.J.) · 2022Article
- Construction of a Glycaemia-Based Signature for Predicting Acute Kidney Injury in Ischaemic Stroke Patients after Endovascular Treatment.Journal of clinical medicine · 2022Article
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with chronic kidney disease have worse outcomes after stroke. However, the burden of acute kidney injury after stroke has not been extensively investigated.
methodsWe used MEDLINE and Embase to conduct a systematic review and meta-analysis of published studies that provided data on the risk of AKI and outcomes in adults after ischemic and hemorrhagic stroke. Pooled incidence was examined using the Stuart-Ord method in a DerSimonian-Laird model. Pooled Odds Ratios and 95% confidence intervals were calculated for outcomes using a random effects model. This review was registered with PROSPERO (CRD42017064588).
resultsEight studies were included, five from the United States, representing 99.9% of included patients. Three studies used established acute kidney injury criteria based on creatinine values to define acute kidney injury and five used International Classification of Diseases coding definitions. Overall pooled incidence was 9.61% (95% confidence interval 8.33-10.98). Incidence for studies using creatinine definitions was 19.51% (95% confidence interval 12.75-27.32%) and for studies using coding definitions 4.63% (95% confidence interval 3.65-5.72%). Heterogeneity was high throughout. Mortality in stroke patients who sustained acute kidney injury was increased (Odds Ratio 2.45; 95% confidence interval 1.47-4.10). Three studies reported risk factors for acute kidney injury. There was sparse information on other outcomes.
conclusionsMortality in stroke patients who develop acute kidney injury is significantly increased. However the reported incidence of AKI after stroke varies widely and is underestimated using coding definitions. Larger international studies are required to identify potentially preventable factors to reduce acute kidney injury after stroke and improve outcomes.
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