Evidence map›Paper›PMID 30347817›Full record

ArticleJournal of clinical medicine2018

Bone Metabolism Markers and Bone Mineral Density in Patients on Long-Term Acenocoumarol Treatment: A Cross-Sectional Study.

Jolanta Sawicka-Powierza, Ewa Jablonska, Wioletta Ratajczak-Wrona, Dorota Rogowska-Szadkowska, Marzena Garley, Alicja M Oltarzewska, Slawomir Chlabicz, Jerzy Konstantynowicz

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jolanta Sawicka-PowierzaDepartment of Family Medicine, Medical University of Bialystok, Bialystok 15-054, Poland. jolasawicka@gmail.com.
Ewa JablonskaDepartment of Immunology, Medical University of Bialystok, Bialystok 15-269, Poland. ewa.jablonska@umb.edu.pl.
Wioletta Ratajczak-WronaDepartment of Immunology, Medical University of Bialystok, Bialystok 15-269, Poland. rwioletta@umb.edu.pl.
Dorota Rogowska-SzadkowskaDepartment of Family Medicine, Medical University of Bialystok, Bialystok 15-054, Poland. dszadkowska@bsk.vectranet.pl.ORCID 0000-0002-2961-4458
Marzena GarleyDepartment of Immunology, Medical University of Bialystok, Bialystok 15-269, Poland. marzena.garley@umb.edu.pl.ORCID 0000-0002-6727-3850
Alicja M OltarzewskaDepartment of Family Medicine, Medical University of Bialystok, Bialystok 15-054, Poland. amoltarz@gmail.com.
Slawomir ChlabiczDepartment of Family Medicine, Medical University of Bialystok, Bialystok 15-054, Poland. schlabicz@poczta.onet.pl.
Jerzy KonstantynowiczDepartment of Pediatric Rheumatology, Immunology, and Metabolic Bone Diseases, Medical University of Bialystok, Bialystok 15-274, Poland. jurekonstant@o2.pl.
Medical University of Białystok · PL

Funding

Uniwersytet Medyczny w Bialymstoku Grant No. 123-04641P
6 · The paper itself

Abstract

The aim of this study was to evaluate levels of osteocalcin (OC), osteoprotegerin (OPG) and total soluble receptor activator of nuclear factor-κB ligand (RANKL), and bone mineral density (BMD) in patients on long-term acenocoumarol (AC) treatment. The cross-sectional study was carried out in 42 patients treated long-term with AC and 28 control subjects. Serum concentrations of OC, OPG, and sRANKL were measured using enzyme linked immunosorbent assay (ELISA) kits, and BMD at the femoral neck and lumbar spine were assessed by dual energy X-ray absorptiometry. A significantly decreased concentration of OC was found in AC users compared to control subjects (4.94 ± 2.22 vs. 10.68 ± 4.5;

Indexed as

acenocoumarolbone metabolismbone mineral densityosteocalcinvitamin K antagonists

Identifiers

PMID30347817
PMCPMC6209941
OpenAlexW2896695067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.