Evidence map›Paper›PMID 30347808›Full record

ArticleInternational journal of molecular sciences2018

C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.

Helene Kolstad Skovdahl, Jan Kristian Damås, Atle van Beelen Granlund, Ann Elisabet Østvik, Berit Doseth, Torunn Bruland, Tom Eirik Mollnes, Arne Kristian Sandvik

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Influence of CTG repeats from the human DM1 locus on murine gut microbiota.Computational and structural biotechnology journal · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Emerging therapeutic options in inflammatory bowel disease.World journal of gastroenterology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Helene Kolstad SkovdahlCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. helene.k.skovdahl@ntnu.no.
Jan Kristian DamåsCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. jan.k.damas@ntnu.no.
Atle van Beelen GranlundCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. atle.granlund@ntnu.no.ORCID 0000-0002-1568-2476
Ann Elisabet ØstvikCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. ann.e.ostvik@ntnu.no.
Berit DosethCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. berit.doseth@ntnu.no.
Torunn BrulandDepartment of Clinical and Molecular Medicine, NTNU, 7030 Trondheim, Norway. torunn.bruland@ntnu.no.ORCID 0000-0002-1568-2476
Tom Eirik MollnesCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. t.e.mollnes@medisin.uio.no.
Arne Kristian SandvikCentre of Molecular Inflammation Research, Norwegian University of Science and Technology (NTNU), 7030 Trondheim, Norway. arne.sandvik@ntnu.no.
Norwegian University of Science and Technology · NOOslo University Hospital · NOSt Olav's University Hospital · NO

Funding

Norges Teknisk-Naturvitenskapelige Universitet 2017/9560/AJThe Liaison Committee between the Central Norway Regional Health Authority and The Norwegian University of Science and Technology https://www.ntnu.no/dmf/rad/samorg
6 · The paper itself

Abstract

The chemokine C-C motif ligand 20 (CCL20) is increased in the colonic mucosa during active inflammatory bowel disease (IBD) and can be found both in the epithelium and immune cells in the lamina propria. The present study investigated CCL20 and C-C motif Chemokine Receptor 6 (CCR6) in peripheral blood mononuclear cells (PBMCs) (

Indexed as

AdultAgedCase-Control StudiesChemokine CCL20Colitis, UlcerativeFemaleHumansInterleukin-1betaMaleMiddle AgedMonocytesNod2 Signaling Adaptor ProteinReceptors, CCR6Toll-Like ReceptorsCCR6 protein, humanChemokine CCL20Interleukin-1betaNOD2 protein, humanNod2 Signaling Adaptor ProteinReceptors, CCR6Toll-Like ReceptorsCCL20CCR6inflammatory bowel diseaseinterleukin-1βperipheral blood mononuclear cells

Identifiers

PMID30347808
PMCPMC6214005
OpenAlexW2896237880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.