Evidence map›Paper›PMID 30347785›Full record

ArticleMarine drugs2018

Increasing Metabolic Diversity in Marine Sponges Extracts by Controlling Extraction Parameters.

Lina M Bayona, Melina Videnova, Young Hae Choi

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Bioactive potency of extracts fromBiomedical reports · 2025
    Article
  4. Article
  5. Synergistic Inhibiting Effect of Phytochemicals inMolecules (Basel, Switzerland) · 2023
    Article
  6. Metabolomics on the study of marine organisms.Metabolomics : Official journal of the Metabolomic Society · 2022
    Review
  7. Review
  8. Article
  9. Antimicrobial Potential and Phytochemical Screening ofBioMed research international · 2021
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Lina M BayonaNatural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands. l.m.bayona.maldonado@biology.leidenuniv.nl.
Melina VidenovaNatural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands. melvidenova@gmail.com.
Young Hae ChoiNatural Products Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE Leiden, The Netherlands. y.choi@chem.leidenuniv.nl.ORCID 0000-0003-1484-1700
Leiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolomics has become an important tool in the search for bioactive compounds from natural sources, with the recent inclusion of marine organisms. Of the several steps performed in metabolomics studies, the extraction process is a crucial step-one which has been overlooked for a long time. In the presented study, a pressurized liquid extraction system was used to investigate the effect of extraction parameters such as pressure, temperature, number of cycles, and solvent polarity on the chemical diversity of the extract obtained from the marine sponge,

Indexed as

AnimalsBiological ProductsEthanolLiquid-Liquid ExtractionMetabolomicsPoriferaProton Magnetic Resonance SpectroscopySolventsTemperatureBiological ProductsEthanolSolvents1H NMRdesign of experimentextractionmarine organismmetabolomic diversity

Identifiers

PMID30347785
PMCPMC6213764
OpenAlexW2896205401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.