Evidence map›Paper›PMID 30347685›Full record

ArticleInternational journal of molecular sciences2018

Sub-Chronic Stress Exacerbates the Pro-Thrombotic Phenotype in BDNF

Leonardo Sandrini, Alessandro Ieraci, Patrizia Amadio, Fabrizio Veglia, Maurizio Popoli, Francis S Lee, Elena Tremoli, Silvia Stella Barbieri

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Dexmedetomidine Reduces Chronic Stress-Related Thrombosis in a Mouse FeClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Cathepsin K deficiency prevented stress-related thrombosis in a mouse FeClCellular and molecular life sciences : CMLS · 2024
    Article
  3. Article
  4. Article
  5. The intriguing role of platelets as custodians of brain-derived neurotrophic factor.Research and practice in thrombosis and haemostasis · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Prenylcysteine Oxidase 1 (PCYOX1), a New Player in Thrombosis.International journal of molecular sciences · 2022
    Article
  10. Article
  11. Review
  12. Depression and Cardiovascular Disease: The Viewpoint of Platelets.International journal of molecular sciences · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Leonardo SandriniDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, 20133 Milan, Italy. leonardo.sandrini@unimi.it.ORCID 0000-0001-9878-8016
Alessandro IeraciDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, 20133 Milan, Italy. alessandro.ieraci@unimi.it.ORCID 0000-0001-6737-7695
Patrizia AmadioCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy. patrizia.amadio@ccfm.it.ORCID 0000-0002-7439-2778
Fabrizio VegliaCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy. fabrizio.veglia@ccfm.it.
Maurizio PopoliDipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, 20133 Milan, Italy. maurizio.popoli@unimi.it.
Francis S LeeDepartment of Psychiatry, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA. fslee@med.cornell.edu.
Elena TremoliCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy. elena.tremoli@ccfm.it.
Silvia Stella BarbieriCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy. silvia.barbieri@ccfm.it.ORCID 0000-0002-7486-2637
Centro Cardiologico Monzino · ITUniversity of Milan · ITCornell University · US

Funding

Italian Ministry of Health "5 × 1000" tax (2013 and 2014)Italian Ministry of Health (Ricerca Corrente) number BIO33-2014: 2607452; BIO35-2015: 2617756; BIO37-2016: 2613074; BIO37-2017: 2631213; MPP1.2A-2018: 2634597
6 · The paper itself

Abstract

Brain-Derived Neurotrophic Factor (BDNF) Val66Met polymorphism has been associated with increased susceptibility to develop mood disorders and recently it has been also linked with cardiovascular disease (CVD). Interestingly, stressful conditions unveil the anxious/depressive-like behavioral phenotype in heterozygous BDNFVal66Met (BDNF

Indexed as

Gene-Environment InteractionAnimalsAortaBone Marrow CellsBrain-Derived Neurotrophic FactorCoronary ThrombosisMaleMiceMutation, MissensePlatelet AggregationStress, PsychologicalBrain-Derived Neurotrophic FactorBDNF Val66Metsub-chronic stressthrombosis

Identifiers

PMID30347685
PMCPMC6214083
OpenAlexW2897129531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.