Evidence map›Paper›PMID 30347674›Full record

ArticleNutrients2018

Effects of Unfiltered Coffee and Bioactive Coffee Compounds on the Development of Metabolic Syndrome Components in a High-Fat-/High-Fructose-Fed Rat Model.

Pedram Shokouh, Per Bendix Jeppesen, Kjeld Hermansen, Christoffer Laustsen, Hans Stødkilde-Jørgensen, Stephen Jacques Hamilton-Dutoit, Mette Søndergaard Schmedes, Haiyun Qi, Thomas Stokholm Nørlinger, Søren Gregersen

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Therapeutic Effects ofNutrients · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Pedram ShokouhDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 165, 8200 Aarhus N, Denmark. Shokouh.P@Gmail.com.ORCID 0000-0002-4514-0045
Per Bendix JeppesenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 165, 8200 Aarhus N, Denmark. per.bendix.jeppesen@clin.au.dk.ORCID 0000-0001-8042-7554
Kjeld HermansenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 165, 8200 Aarhus N, Denmark. kjeld.hermansen@aarhus.rm.dk.
Christoffer LaustsenMR Research Centre, Aarhus University Hospital Skejby, Palle Juul Jensens Boulevard 99, 8200 Aarhus N, Denmark. cl@clin.au.dk.ORCID 0000-0002-0317-2911
Hans Stødkilde-JørgensenMR Research Centre, Aarhus University Hospital Skejby, Palle Juul Jensens Boulevard 99, 8200 Aarhus N, Denmark. hsj@clin.au.dk.
Stephen Jacques Hamilton-DutoitInstitute of Pathology, Aarhus University Hospital Skejby, Palle Juul Jensens Boulevard 99, 8200 Aarhus N, Denmark. stephami@rm.dk.
Mette Søndergaard SchmedesDepartment of Food Science, Aarhus University, 5792 Årslev, Denmark. mette.schmedes@food.au.dk.ORCID 0000-0003-3475-8250
Haiyun QiMR Research Centre, Aarhus University Hospital Skejby, Palle Juul Jensens Boulevard 99, 8200 Aarhus N, Denmark. qi@clin.au.dk.
Thomas Stokholm NørlingerMR Research Centre, Aarhus University Hospital Skejby, Palle Juul Jensens Boulevard 99, 8200 Aarhus N, Denmark. thomasnorlinger@gmail.com.
Søren GregersenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 165, 8200 Aarhus N, Denmark. soeren.gregersen@aarhus.rm.dk.
Aarhus University Hospital · DKAarhus University · DKOdense University Hospital · DK

Funding

Aarhus Universitets Forskningsfond Doctoral FellowshipDanish Diabetes Academy supported by the Novo Nordisk Foundation Doctoral FellowshipInnovation Fund Denmark 1308-00028BRiisfort Fonden Research Grant
6 · The paper itself

Abstract

The literature is inconsistent as to how coffee affects metabolic syndrome (MetS), and which bioactive compounds are responsible for its metabolic effects. This study aimed to evaluate the effects of unfiltered coffee on diet-induced MetS and investigate whether or not phenolic acids and trigonelline are the main bioactive compounds in coffee. Twenty-four male Sprague‒Dawley rats were fed a high-fat (35% W/W) diet plus 20% W/W fructose in drinking water for 14 weeks, and were randomized into three groups: control, coffee, or nutraceuticals (5-

Indexed as

CoffeeAlkaloidsAnimalsBlood GlucoseBody WeightCaffeic AcidsDietary CarbohydratesDietary SupplementsDiet, High-FatEatingFructoseInsulin ResistanceMaleMetabolic SyndromeQuinic AcidRandom AllocationAlkaloidsBlood Glucosecaffeic acidCaffeic Acidscaffeoylquinic acidCoffeeDietary CarbohydratesFructoseQuinic Acidtrigonellinecaffeic acidcarbon-13 magnetic resonance spectroscopychlorogenic acidcoffeeinsulin resistancemetabolic syndrome xnon-alcoholic fatty liver diseasephytotherapytrigonelline

Identifiers

PMID30347674
PMCPMC6213813
OpenAlexW2888290927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.