Evidence map›Paper›PMID 30347272›Full record

ArticleJournal of cardiac failure2019

Hydrogen- and Methane-Based Breath Testing and Outcomes in Patients With Heart Failure.

Anna Mollar, Maria Pilar Villanueva, Eduardo NÚÑez, Arturo CarratalÁ, Francisco Mora, Antoni BayÉs-GenÍs, Miguel MÍnguez, Vannina G Marrachelli, Daniel Monleon, David Navarro and 2 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiac failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Anna MollarCardiology Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain.
Maria Pilar VillanuevaServicio de Bioquímica Clínica, Hospital Clínico Universitario, Universitat de Valencia, INCLIVA, Valencia, Spain.
Eduardo NÚÑezCardiology Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain.
Arturo CarratalÁServicio de Bioquímica Clínica, Hospital Clínico Universitario, Universitat de Valencia, INCLIVA, Valencia, Spain.
Francisco MoraDigestive Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain.
Antoni BayÉs-GenÍsCIBER Cardiovascular, Madrid, Spain; Cardiology Service and Heart Failure Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; and Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain.
Miguel MÍnguezDigestive Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain.
Vannina G MarrachelliMetabolomic and Molecular Image Lab, Health Research Institute, INCLIVA, Valencia, Spain.
Daniel MonleonMetabolomic and Molecular Image Lab, Health Research Institute, INCLIVA, Valencia, Spain; Pathology Department, Universitat de València, Valencia, Spain.
David NavarroMicrobiology Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain.
Juan SanchisCardiology Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain; CIBER Cardiovascular, Madrid, Spain.
Julio NÚÑezCardiology Department, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain; CIBER Cardiovascular, Madrid, Spain. Electronic address: yulnunez@gmail.com.
Universitat de València · ESINCLIVA Health Research Institute · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent evidence endorses gut microbiota dysregulation in the pathophysiology of heart failure (HF). Small intestinal bacterial overgrowth (SIBO) might be present in HF and associated with poor clinical outcomes. Lactulose breath testing is a simple noninvasive test that has been advocated as a reliable indicator of SIBO. In patients with HF, we aimed to evaluate the association with clinical outcomes of the exhaled hydrogen (H METHODS AND

resultsWe included 102 patients with HF in which lactulose SIBO breath tests were assessed. Cumulative gas was quantified by the area under the receiver operating characteristic curve of CH

conclusionsAUC-H

Indexed as

Breath TestsAgedAged, 80 and overBacteriaExhalationFemaleFollow-Up StudiesGastrointestinal MicrobiomeHeart FailureHospitalizationHumansHydrogenIntestine, SmallMaleMethaneProspective StudiesHydrogenMethanebreath testsGutheart failureprognosissmall intestinal bacterial overgrowth

Identifiers

PMID30347272
OpenAlexW2896917218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.