Evidence map›Paper›PMID 30347074›Full record

ArticleInvestigative ophthalmology & visual science2018

Dim Light Exposure and Myopia in Children.

Erica G Landis, Victoria Yang, Dillon M Brown, Machelle T Pardue, Scott A Read

Open access · goldAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. The Effect of Light Intensity and the Timing of Light Exposure on Choroidal Thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Trial
  3. Review
  4. Mesopic Illumination in Natural Environments: Implications for Myopia Research.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  5. Review
  6. Article
  7. Circadian rhythms regulate refractive development across species.bioRxiv : the preprint server for biology · 2026
    Article
  8. RLRL Therapeutic Feasibility and Potential Mechanism on Myopia.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Measuring the visual environment of children and young people at risk of myopia: a scoping review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  16. Modulation of All-Trans Retinoic Acid by Light and Dopamine in the Murine Eye.Investigative ophthalmology & visual science · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Erica G LandisNeuroscience, Emory University, Atlanta, Georgia, United States.
Victoria YangAtlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States.
Dillon M BrownAtlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States.
Machelle T PardueNeuroscience, Emory University, Atlanta, Georgia, United States.
Scott A ReadSchool of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia.
Georgia Institute of Technology · USVeterans Health Administration · USQueensland University of Technology · AU

Funding

P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
Neuromodulators and Circadian Clocks: Roles in Retinal Function and DysfunctionR01EY004864 · NEI · EMORY UNIVERSITY · PI IUVONE, P MICHAEL · 1985 to 2018
$7.0M
Retinal Mechanisms of Refractive DevelopmentR01EY016435 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI Machelle T. Pardue · 2009 to 2026
$5.4M
VIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6M
Retinal circadian rhythms and refractive developmentR01EY022342 · NEI · UNIVERSITY OF PENNSYLVANIA · PI STONE, RICHARD A · 2013 to 2015
$1.7M
NEI NIH HHS P30 EY006360NEI NIH HHS R01 EY004864NEI NIH HHS R01 EY016435NEI NIH HHS R01 EY022342NEI NIH HHS T32 EY007092
6 · The paper itself

Abstract

Purpose: Experimental myopia in animal models suggests that bright light can influence refractive error and prevent myopia. Additionally, animal research indicates activation of rod pathways and circadian rhythms may influence eye growth. In children, objective measures of personal light exposure, recorded by wearable light sensors, have been used to examine the effects of bright light exposure on myopia. The effect of time spent in a broad range of light intensities on childhood refractive development is not known. This study aims to evaluate dim light exposure in myopia. Methods: We reanalyzed previously published data to investigate differences in dim light exposure across myopic and nonmyopic children from the Role of Outdoor Activity in Myopia (ROAM) study in Queensland, Australia. The amount of time children spent in scotopic (<1-1 lux), mesopic (1-30 lux), indoor photopic (>30-1000 lux), and outdoor photopic (>1000 lux) light over both weekdays and weekends was measured with wearable light sensors. Results: We found significant differences in average daily light exposure between myopic and nonmyopic children. On weekends, myopic children received significantly less scotopic light (P = 0.024) and less outdoor photopic light than nonmyopic children (P < 0.001). In myopic children, more myopic refractive errors were correlated with increased time in mesopic light (R = -0.46, P = 0.002). Conclusions: These findings suggest that in addition to bright light exposure, rod pathways stimulated by dim light exposure could be important to human myopia development. Optimal strategies for preventing myopia with environmental light may include both dim and bright light exposure.

Indexed as

Activities of Daily LivingAdolescentChildCircadian RhythmColor VisionEnvironmental ExposureFemaleHumansMaleMesopic VisionMyopiaNight VisionPhotoreceptor Cells, VertebrateRefraction, OcularVision Tests

Identifiers

PMID30347074
PMCPMC6181186
OpenAlexW2896581134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.