Evidence map›Paper›PMID 30345745›Full record

ArticleBiochemistry2018

A Quantitative Model for BicD2/Cargo Interactions.

Crystal R Noell, Kyle M Loftus, Heying Cui, Christof Grewer, Megan Kizer, Erik W Debler, Sozanne R Solmaz

Abstract read
In one paragraph

Article in Biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Crystal R NoellDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.
Kyle M LoftusDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.
Heying CuiDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.
Christof GrewerDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.ORCID 0000-0002-8342-9878
Megan KizerDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.
Erik W DeblerDepartment of Biochemistry & Molecular Biology , Thomas Jefferson University , Philadelphia , Pennsylvania 19107 , United States.
Sozanne R SolmazDepartment of Chemistry , State University of New York at Binghamton , Binghamton , New York 13902 , United States.ORCID 0000-0002-1703-3701

Funding

Cell cycle-specific recognition of the cell nucleus as cargo for dynein-dependent transportR15GM128119 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI SOLMAZ, SOZANNE R · 2018 to 2018
$449k
NIGMS NIH HHS R15 GM128119
6 · The paper itself

Abstract

Dynein adaptor proteins such as Bicaudal D2 (BicD2) are integral components of the dynein transport machinery, as they recognize cargoes for cell cycle-specific transport and link them to the motor complex. Human BicD2 switches from selecting secretory and Golgi-derived vesicles for transport in G1 and S phase (by recognizing Rab6

Indexed as

Biological TransportCell NucleusHeLa CellsHumansMicrotubule-Associated ProteinsModels, MolecularMolecular ChaperonesNuclear Pore Complex Proteinsrab GTP-Binding ProteinsBICD2 protein, humanMicrotubule-Associated ProteinsMolecular ChaperonesNuclear Pore Complex ProteinsRab6 proteinrab GTP-Binding Proteinsran-binding protein 2

Identifiers

PMID30345745
PMCPMC6520106

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.