Evidence map›Paper›PMID 30345461›Full record

ArticleJournal of molecular neuroscience : MN2018

Euxanthone Attenuates Aβ

Haicheng Yuan, Chuanwu Jiang, Jingde Zhao, Yunsheng Zhao, Yongbin Zhang, Yanqi Xu, Xiaoning Gao, Lingfei Guo, Yongji Liu, Kai Liu and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Haicheng YuanDepartment of Neurology, Qingdao Central Hospital, Qingdao, Shandong, China.
Chuanwu JiangDepartment of Interventional Radiology, Jinan Military General Hospital, Shifan Road 25, Tianqiao District, Jinan, 250000, Shandong, China.
Jingde ZhaoDepartment of Interventional Radiology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Yunsheng ZhaoDepartment of Endocrinology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Yongbin ZhangDepartment of Interventional Radiology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Yanqi XuDepartment of Interventional Radiology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Xiaoning GaoDepartment of Interventional Radiology, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Lingfei GuoDepartment of Interventional Radiology, Shandong Medical Imaging Research Institute, Jinan, Shandong, China.
Yongji LiuDepartment of Neurosurgery, Qingdao Hospital of Traditional Chinese Medicine, Qingdao, Shandong, China.
Kai LiuDepartment of Interventional Radiology, Jinan Military General Hospital, Shifan Road 25, Tianqiao District, Jinan, 250000, Shandong, China.
Bo XuDepartment of Neurology, Qingdao Central Hospital, Qingdao, Shandong, China. boxuqdhc@126.com.
Gang SunDepartment of Interventional Radiology, Jinan Military General Hospital, Shifan Road 25, Tianqiao District, Jinan, 250000, Shandong, China. gangsunqdhc@126.com.ORCID http://orcid.org/0000-0002-1640-7716
Qingdao University · CNJinan Military General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common neurodegenerative disorder and is characterized by the deposition of β-Amyloid (Aβ) plaques which contribute to its pathology. The present study was aimed at exploring the protective effects of euxanthone against Aβ-induced neurotoxicity both in vivo and in vitro. We found that euxanthone significantly attenuated Aβ

Indexed as

ApoptosisAutophagyAlzheimer DiseaseAmyloid beta-PeptidesAnimalsAntioxidantsHippocampusMaleNeuroprotective AgentsOxidative StressPC12 CellsPeptide FragmentsRatsRats, Sprague-DawleyXanthonesAmyloid beta-Peptidesamyloid beta-protein (1-42)AntioxidantseuxanthoneNeuroprotective AgentsPeptide FragmentsXanthonesAlzheimer’s diseaseAutophagyEuxanthone

Identifiers

PMID30345461
OpenAlexW2897635829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.